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Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Flutamide may slightly improve hair loss in women, but finasteride does not work.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.

Higher fluence in hair removal damages hair follicles more, while lower fluence mimics natural hair regression, with long-term IPL treatments effectively reducing hair.

Urologists should screen for mental health issues before and during finasteride treatment.

Hesperidin helps protect against testicular damage caused by finasteride.

Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Gene differences may affect baldness treatment response in Korean men.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

Dutasteride is more effective than finasteride for hair loss treatment.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.

Combining fractional CO2 laser with topical dutasteride is more effective for treating male hair loss than using the laser alone.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The study created a new method to test drugs that affect hormone processing in skin.

Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.