12 citations
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July 2017 in “Scientific reports” In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.
1 citations
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June 2003 in “Obstetrical & Gynecological Survey” This new method makes checking for female infertility less painful, less invasive, and doesn't use radiation.
6 citations
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January 2011 in “PubMed” This paper reviews hair loss associated with various endocrine disorders and describes both traditional and emerging non-invasive diagnostic methods without presenting any new clinical results.
4 citations
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May 2021 in “Molecules” This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.
August 2026 in “Frontiers in Surgery” This review article from the examined literature highlights the shift in eyebrow reconstruction techniques from traditional methods to minimally invasive and regenerative approaches, evaluating their principles, outcomes, and challenges to inform future clinical practices.
June 2026 in “Vestnik dermatologii i venerologii” This study evaluated the use of Jet Peel technology, a non-invasive hydroporation method, in treating androgenetic and telogen effluvium alopecia, finding improvements in hair growth and thickness, and a reduction in associated scalp conditions.
September 2023 in “Biomedical Optics Express” This study used non-invasive imaging techniques to assess hair follicle characteristics in AGA mice, revealing delayed hair shaft alternation and growth stages, as well as testosterone-induced follicle miniaturization, offering potential methods for evaluating AGA on human scalps in vivo.
11 citations
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June 2012 in “Human Reproduction Update” This review discusses recent advancements in female contraception and covers topics like adapted regimens, non-invasive sterilization, and the promise of new methods, but it reports no new clinical findings.
153 citations
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August 2002 in “Dermatologic Surgery” This paper introduces the Follicular Unit Extraction procedure and its accompanying FOX Test, finding that 60% of tested patients were suitable candidates for this minimally invasive hair transplantation method.
14 citations
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January 2003 in “Skin Research and Technology” This study found that the scalp coverage scoring (SCS) method is a non-invasive and reproducible technique that effectively measures hair growth and loss dynamics in male subjects with androgenetic alopecia.
12 citations
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January 2009 in “Breast Cancer Basic and Clinical Research” This study found that the combination of mammography and hair X-ray diffraction increased sensitivity for detecting breast cancer compared to using each method alone.
6 citations
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September 2025 in “Scientific Reports” This study found that using XGBoost with clinical and ultrasound features may provide a highly accurate, non-invasive method for diagnosing polycystic ovary syndrome, although further validation is needed to ensure robustness.
7 citations
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July 2018 in “Stem cell research” This study reported that reprogramming keratinocytes from plucked hair provides an easy, non-invasive, and efficient method for generating pluripotent iPSCs without the need for medical professionals or operating rooms.
1 citations
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March 2024 in “arXiv (Cornell University)” This paper presents a new method using Convolutional Neural Networks for detecting hair and scalp diseases, aiming to enhance diagnostics accessibility through a web-based platform integration.
January 2026 in “Journal of Hair Restoration and Regenerative Medicine” This review discusses methods to better identify unsafe donor areas in patients with diffuse unpatterned alopecia, emphasizing non-surgical management when specific diagnostic criteria are met, but reports no new clinical results.
10 citations
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March 2022 in “Communications biology” In this study, researchers found that non-invasive analysis of skin surface lipid RNAs revealed alterations in gene expression patterns associated with atopic dermatitis, suggesting its potential for understanding skin disease pathophysiology.
September 2023 in “Stem cell reviews and reports” This study introduces a new method to isolate stem cells from the hair follicle outer root sheath of equine skin, demonstrating that these cells, named eMSCORS, proliferate efficiently and can differentiate similarly to adipose tissue-derived MSCs, offering a promising alternative for equine veterinary applications.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a partially automated protocol utilizing hair follicles for DNA extraction in marmosets, achieving reliable whole genome sequencing with low chimerism, offering an efficient alternative to blood for genetic studies in non-human primates.
1 citations
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January 2006 in “Dermatologic Surgery” The SAFE System may reduce hair transplant transection rates but has been critiqued for not being as minimally invasive as claimed.
This study developed a convolutional neural network model for non-invasive diagnosis of androgenetic alopecia using dermoscopic images, demonstrating potential accuracy and scalability while highlighting the importance of model interpretability for clinical use.
October 2024 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that trichoscopy can effectively identify specific patterns associated with Vitamin B12, Vitamin D3, and serum ferritin deficiencies in patients with Telogen Effluvium, offering a non-invasive alternative to blood tests for early diagnosis and management.
December 2025 in “Progress in Biomedical Engineering” This article reviews emerging mechanobiological strategies like electrical stimulation and microneedling combined with nanotechnology as non-invasive methods for hair loss treatment, suggesting these approaches could provide futuristic alternatives to current therapies such as minoxidil, finasteride, and hair transplants.
January 2024 in “Revue médicale suisse” This article reviews current treatment options for androgenetic alopecia, assessing the efficacy and potential side effects of medications and minimally-invasive strategies like photobiomodulation, micro-needling, and platelet-rich plasma therapy, while also discussing hair transplantation and camouflage methods.
1 citations
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November 2021 in “IntechOpen eBooks” This review covers red light Transcranial LED therapy for hippocampal memory impairment in aging and Alzheimer's but reports no clinical results, highlighting a need for further research into its mechanisms and effects.
192 citations
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April 2019 in “ACS nano” In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
63 citations
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February 2003 in “Australasian Journal of Dermatology” This review discusses various methods for measuring scalp hair growth in androgenetic alopecia and reports no new results; the authors suggest that computer-assisted technology has untapped potential.
17 citations
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January 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” Isoconazole nitrate stays effective in skin and hair follicles for up to two weeks after use.
5 citations
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February 2014 in “PubMed” This review highlights the need for standardization of diagnostic techniques for hair diseases and emphasizes their importance in distinguishing conditions and monitoring treatment effects, but it reports no new experimental results.
3 citations
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October 2019 in “Pharmaceutics” This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.
3 citations
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October 2006 in “Journal of dermatology” This study reported that X-ray microscopy provides more intact images of hair's internal structure compared to transmission electron microscopy, particularly for observing fine details like cuticle coarsening and cortex cracks.