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This study found that exposure to sex steroid biosynthesis inhibitors increases the expression of piRNA pathway genes in frog larvae, suggesting these genes play a role in gonadal sex differentiation.

This case study highlights the complexity of managing PCOS and its symptoms in transmen, suggesting hormonal fluctuations may lead to symptomatic relief with low dose estradiol.

This case report highlights the importance of considering an ovarian steroid cell tumor diagnosis in young women with increased testosterone after ruling out polycystic ovarian syndrome.

This case report from a German study detailed a 2-year-old girl with virilization and precocious puberty due to a rare ovarian steroid cell tumor, finding that post-surgery, her elevated hormone levels normalized within a week, and ongoing follow-up showed no need for chemotherapy.

This article explores the mechanisms of female hirsutism and highlights the effectiveness of eflornithine in reducing hair growth, with further removal requiring physical methods.

This case report describes a 22-year-old woman with hirsutism and irregular menstrual bleeding, diagnosed with an ovarian steroid cell tumor (NOS), whose androgen levels normalized after surgery.

This study suggests that in rats, maternal hyperandrogenism and insulin resistance lead to activation of ferroptosis in the gravid uterus and placenta, mediated by different molecular and cellular mechanisms.

In this case series study, two Peruvian women with virilizing ovarian tumors called Sertoli-Leydig cell tumors showed clinical improvement and normalization of androgens after surgical treatment, highlighting the diagnostic challenge of these rare presentations at different ages.

This review discusses the molecular mechanisms of masculinization involving androgen signaling and their roles in male embryonic development and conditions like hypospadias and prostate cancer, and reports no clinical results.

In this study, transvaginal hydrolaparoscopy ovarian drilling in CC-resistant women with PCOS significantly improved ovulation and pregnancy rates over a six-month period, with 82.9% ovulating and a 70.1% pregnancy rate by the end of the study.

This case study reported that sudden hyperandrogenism in postmenopausal women may indicate hormonally active ovarian tumors such as Leydig cell tumors, which can be effectively treated with surgery.

This study discovered that TTR is expressed in the human placenta as early as 6 weeks gestation, with increased levels in the first trimester potentially facilitating thyroid hormone delivery to the fetus.

This case report highlights a Palestinian woman with a rare ovarian steroid cell tumor, underscoring the diagnostic challenges and potential for disease progression despite treatment attempts with various chemotherapy regimens.

This case study reported that a 51-year-old woman with hirsutism and voice thickening had a Leydig cell tumor detected by PET-CT, which normalized hormone levels and resolved symptoms after surgical removal.

This study evaluated 23 cases of MRKH syndrome undergoing neo-vaginal reconstruction using islanded pudendal thigh flaps, finding a 100% flap survival and patency rate, along with satisfactory functional and aesthetic outcomes despite minor issues like hair growth in some patients.

This case report describes a 57-year-old woman's virilizing adrenal tumor effectively treated with the antiandrogen cyproterone acetate, which led to symptom reversal and tumor resolution.

This case report describes a woman with virilization syndrome who experienced a reduction in androgen levels and reversal of alopecia after removal of a Leydig cell tumor from her ovary.

This study found that chronic exposure to fadrozole or finasteride during frog development induced intersex individuals, which displayed different gene expression profiles depending on the chemical used.

This study reported that treatment with cyproterone acetate alone and then with incremental estrogen doses induced mild feminizing effects in late-pubertal trans-girls, with further feminization observed after adding estrogen.

This report describes a complex case of postmenopausal hyperandrogenism with virilization and concurrent rare ovarian tumors, highlighting the critical role of interdisciplinary collaboration in diagnosing and managing such challenging scenarios.

This case report describes a 64-year-old postmenopausal woman with hirsutism due to a rare case of bilateral diffuse ovarian Leydig cell hyperplasia, leading to normalized testosterone levels and improved glycaemic control following surgery.

This case report highlights a rare diagnosis of an androgen-secreting adrenal tumor in a patient with hyperandrogenism and virilization symptoms, emphasizing the role of gynecologists in early detection.

A rare pancreatic tumor caused a woman's male-like features, treated successfully with surgery and medication.

This case report describes Ayurvedic treatment, including Samshodhan Karma and Shaman Chikitsa, that resulted in pregnancy for a 22-year-old woman with PCOS-related infertility after 3 years of trying to conceive.

This study found that penile and clitoral differentiation in mice is influenced by androgen exposure, with penile features developing postnatally requiring prenatal and ongoing androgen presence.

This study of monozygotic transgender male twins observed that consistent hormone therapy led to physical changes such as deepening voice and increased facial/body hair, with no reported mood-related adverse effects.

This study found that cyproterone acetate treatment in late-pubertal trans-girls was safe, well-tolerated, and induced mild feminizing changes, with more pronounced effects when combined with estrogens.

This case study reports the first Palestinian case of an ovarian steroid cell tumor with virilization in a young female, highlighting the challenges in diagnosis and varied chemotherapeutic responses.

This case report describes a 60-year-old woman with an ovarian Leydig cell tumor leading to elevated testosterone levels and hirsutism, highlighting the need to consider androgen-secreting tumors in similar postmenopausal cases.

In this study, micro-CT analysis revealed that severe hypospadias in finasteride-induced rats was associated with varying levels of preputial blood circulation, impacting potential surgical approaches.