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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Some skin conditions are common during pregnancy and can be safely treated without affecting the pregnancy outcome.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

COVID-19 may harm male fertility and damage the reproductive system.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.

Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

A 1-day or 3-day itraconazole treatment is effective for acute vulvovaginal candidosis, but recurrent cases may need longer treatment.

Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.

Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.