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Knuckle darkening can be an early sign of vitamin B12 deficiency.

The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.

Experts discussed treatments for skin conditions in children, emphasizing hydration, cautious medication use, and early intervention for infections.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

No systemic treatment for alopecia areata has strong evidence of effectiveness.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

Hair loss in lupus is different from hair loss in alopecia areata and may indicate lupus activity.

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

Captopril may cause hair loss, as shown by a woman's hair regrowing after stopping the medication.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

The article compares different products for rejuvenating the upper part of the face.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Using minoxidil before and after facelift surgery can effectively prevent temporary hair loss without causing other complications.