Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study developed microneedles loaded with Platycladus orientalis leaf extract to treat androgenic alopecia, finding that they can effectively deliver active ingredients into the dermis, promote hair follicle growth by removing free radicals, and activate the Wnt/β-catenin pathway.

In this study, Platycladus orientalis leaf extract loaded into hyaluronic acid microneedles was found to promote hair follicle growth by enhancing the environment for hair cell proliferation and activating repair pathways, suggesting potential as a treatment for androgenic alopecia.

This article reviews the promising ease of drug administration via transdermal and other topical routes, highlighting their potential for high patient compliance and reduced side effects but provides no new clinical results.

This article reviews recent imaging and genetic tool advances that enable in vivo study of hair regeneration and assessment of skin parameters, but it reports no new clinical results.

This study reviews recent advancements in microneedles made from PLGA, highlighting their use in delivering vaccines, drugs, and proteins through the skin with minimal invasiveness, and discusses the challenges and future potential of these delivery systems.

This review highlights the promising potential of mesotherapy for delivering dutasteride and minoxidil as treatments for androgenetic alopecia, emphasizing the need for more research on drug preparation, delivery, and maintenance to establish its safety and effectiveness.

This study found that using a combination of iontophoresis and liposomal delivery facilitated the effective intradermal administration of superoxide dismutase in rats, reducing oxidative skin damage from UV exposure.

This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.

In this study on mice, a baricitinib-loaded microneedle patch enhanced hair growth in alopecia areata lesions (68% vs control: 33%, p < 0.05), suggesting it may deliver treatment effectively and pain-free, with fewer systemic side effects.

This review found that platelet-rich plasma shows potential in improving melasma, though its overall benefit varies across different treatment methods and may not enhance results when combined with certain other treatments.

In this study, researchers developed a new self-administered finasteride delivery system using powder-carrying microneedles that improved hair growth efficacy and addressed safety concerns compared to topical finasteride gel by allowing sustained intradermal release of the drug for three days with a single application.

In this study, researchers developed a new microneedle patch delivery system for minoxidil, which enhanced its controlled release and improved hair growth in mice, potentially offering better treatment outcomes for androgenetic alopecia.

This study demonstrated that novel cryomicroneedles loaded with hair follicle organoids (cryoMN@HFOs) can effectively deliver and develop into functional hair follicles after intradermal transplantation in animal experiments, suggesting promising potential for human hair follicle reconstruction.

This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.

This review highlights the potential of microneedle devices in dermatology for conditions like skin aging and autoimmune skin diseases, emphasizing their ability to facilitate targeted drug delivery by creating temporary skin pathways.

This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.

This review discusses the development and applications of microneedles, particularly through 3D printing, highlighting their potential in transdermal drug delivery but reporting no new results.

This article discusses the benefits of liposomes in cosmetic formulations, including enhanced hydration and protection for dry skin, but reports no new experimental findings.

This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.

This study found that PRP was effective for treating alopecia areata with similar improvement across groups, while topical delivery via fractional CO2 laser or microneedling reduced injection pain.

This study demonstrated that adapalene encapsulated in liposomes significantly improved drug delivery to hair follicles compared to gel and drug solution, potentially targeting acne treatment more effectively.

Smart microneedles using advanced tech could improve psoriasis treatment.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.

A new microneedle system may improve hair loss treatment by delivering ketoconazole directly to hair follicles.

This review highlights recent advances in personalized transdermal drug delivery systems, noting their potential for improved treatment efficacy and safety, but identifies significant challenges in clinical translation.

This review explores how nanoparticles enhance cosmeceutical formulations, analyzing their roles in transporting active ingredients, and highlights the progress and challenges in using nanotechnology for beauty and health products.

This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

This review summarizes recent advances in alopecia management, focusing on combining synthetic and herbal therapies with innovative drug delivery systems like nanocarriers to enhance effectiveness and reduce side effects, while noting challenges with skin penetration and bioavailability.