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    Did you mean Insulin-like Growth Factor 1?
    Glossary Insulin-like Growth Factor 1

    hormone promoting cell growth and development, similar to insulin

    Insulin-like Growth Factor 1 (IGF-1) is a hormone similar in structure to insulin that plays a crucial role in childhood growth and continues to have anabolic effects in adults. It is primarily produced in the liver and is stimulated by growth hormone (GH). IGF-1 is involved in cell growth, development, and repair, and has been studied for its potential effects on hair growth and the treatment of conditions like alopecia.

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    1. 411 The efficacy of 1550-nm erbium-glass fractional laser treatment and its effect on the expression of insulin-like growth factor 1 and Wnt/β-catenin in androgenetic alopecia Journal of Investigative Dermatology · 2018
    2. Astragalus membranaceus and Cinnamomum cassia Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/β-Catenin Signaling Pathway Current Issues in Molecular Biology · 2023
    3. Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells International Journal of Molecular Sciences · 2020 · 8 citations
    4. Role of insulin, insulin‐like growth factor‐1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris Experimental dermatology · 2009 · 200 citations
    5. Insulin-like growth factor 1 and hair growth Dermatology Online Journal · 1999 · 98 citations
    6. Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth The Korean Journal of Physiology and Pharmacology · 2018 · 21 citations
    7. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/β-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    8. Activation of Hair Cell Growth Factors by Linoleic Acid in Malva verticillata Seed 2021 · 17 citations
    9. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    10. 1017 The prostaglandin F2α analog bimatoprost activates secondary hair germ cells to promote hair growth through two distinct signaling pathways Journal of Investigative Dermatology · 2026
    11. 3-Hydroxypropionic Acid Enhances Hair Growth-Related Signaling in Human Follicle Dermal Papilla Cells via Activation of the Wnt/β-Catenin Pathway International Journal of Molecular Sciences · 2026
    12. Cashmere growth control in Liaoning cashmere goat by ovarian carcinoma immunoreactive antigen-like protein 2 and decorin genes Asian-Australasian journal of animal sciences · 2018 · 7 citations
    13. 562 Neuroendocrinology of human scalp hair follicles: Growth hormone-releasing hormone (GHRH) stimulates hair growth and controls a fully functional intrafollicular hypothalamic-pituitary-somatotropic (HPS) signaling axis Journal of Investigative Dermatology · 2022
    14. 730 M2 macrophages promote wound induced hair neogenesis through the production of growth factors 2016
    15. Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021 · 14 citations
    16. A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control Experimental Dermatology · 2004 · 2 citations
    17. Inducing hair follicle organogenesis with defined environmental protein factors Journal of Dermatological Science · 2016
    18. Effect of Scenedesmus deserticola JD052 Extracts on Hair Inductivity by Regulating the AKT and GSK3β/β-Catenin Signaling Pathways in Human Dermal Papilla Cells Applied Sciences · 2025
    19. Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties Frontiers in Veterinary Science · 2023 · 5 citations
    20. Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin PLOS ONE · 2015 · 32 citations
    21. Hair Growth Promoting Effects of Limosilactobacillus reuteri Isolated from Honeybee through Wnt/β-catenin Signal Transduction Journal of the Korean Society of Cosmetology · 2026
    22. Regulation of human hair growth: hormones and neuropeptides 프로그램북(구 초록집) · 2016
    23. Role of insulin resistance and diet in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 39 citations
    24. Monoterpenoid Loliolide Regulates Hair Follicle Inductivity of Human Dermal Papilla Cells by Activating the Akt/ ¥-Catenin Signaling Pathway Journal of Microbiology and Biotechnology · 2019 · 37 citations
    25. Effect of sinapic acid on hair growth promoting in human hair follicle dermal papilla cells via Akt activation Archives of Dermatological Research · 2017 · 25 citations
    26. The effects of centipedegrass extract on hair growth via promotion of anagen inductive activity PLoS ONE · 2022 · 6 citations
    27. Vitamin A regulates dermal papilla cell proliferation and apoptosis under heat stress via IGF1 and Wnt10b signaling Ecotoxicology and environmental safety · 2023 · 2 citations
    28. MLPH-mediated activation of dermal papilla IGF-1 signaling drives human hair shaft elongation and anagen induction Biomedicine & Pharmacotherapy · 2026
    29. Enhancing hair growth through phytochemicals: mechanisms, supporting evidence, and future directions Journal of Pharmacy and Pharmacology · 2025
    30. Hair Growth Effect and the Mechanisms of Rosa rugosa Extract in DHT-Induced Alopecia Mice Model International Journal of Molecular Sciences · 2024