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    Glossary Insulin-like Growth Factor Binding Proteins

    regulate insulin-like growth factors' activity and availability

    Insulin-like Growth Factor Binding Proteins (IGFBPs) are a group of proteins that bind to insulin-like growth factors (IGFs), which are hormones involved in growth and development. By binding to IGFs, IGFBPs regulate their activity, availability, and interaction with IGF receptors, thereby playing a crucial role in cell growth, differentiation, and metabolism.

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    1. Regulation of human dermal papilla cell production of insulin-like growth factor binding protein-3 by retinoic acid, glucocorticoids, and insulin-like growth factor-1 Journal of cellular physiology · 1996 · 37 citations
    2. Study on Expression of Insulin-like Growth Factor-binding Protein-3and -5(IGFBP-3 and IGFBP-5)in the Skin of Inner Mongolia Cashmere Goat China Animal Husbandry & Veterinary Medicine · 2013
    3. Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil). Endocrinology · 1999 · 43 citations
    4. Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3 Journal of The American Academy of Dermatology · 2000 · 26 citations
    5. Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3 Journal of The American Academy of Dermatology · 2000 · 3 citations
    6. The Association Between Low (Or Reduced) Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 with Hair Loss in Women. A Case- Control Study in Basrah City of Iraq Zenodo (CERN European Organization for Nuclear Research) · 2026
    7. The Association Between Low (Or Reduced) Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 with Hair Loss in Women. A Case- Control Study in Basrah City of Iraq Zenodo (CERN European Organization for Nuclear Research) · 2026
    8. The Association between Low (or Reduced) Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 with Hair Loss in Women. A Case-Control Study in Basrah, Iraq European Journal of Medical and Health Research · 2026
    9. Insulin-like growth factor 1 and hair growth Dermatology Online Journal · 1999 · 98 citations
    10. Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth The Korean Journal of Physiology and Pharmacology · 2018 · 21 citations
    11. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    12. Insulin-like growth factor-1: roles in androgenetic alopecia Experimental Dermatology · 2014 · 27 citations
    13. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015 · 17 citations
    14. Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration ACS Applied Bio Materials · 2019 · 5 citations
    15. Subcutaneous injection of conditioned medium from photobiomodulation-treated adipose-derived stromal cells promotes hair growth and angiogenesis in mice Archives of Dermatological Research · 2025
    16. Hair Growth-Promoting Activity of Citron Seed Oil: Induction of Premature Telogen-To-Anagen Transition of Hair Follicle in C57BL/6 Mouse Models Current Topics in Nutraceutical Research · 2021
    17. (Neuro-)endocrinology of epithelial hair follicle stem cells Molecular and Cellular Endocrinology · 2008 · 42 citations
    18. Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy Stem Cell Research & Therapy · 2020 · 20 citations
    19. Intrauterine botulinum toxin A administration promotes endometrial regeneration mediated by IGFBP3-dependent OPN proteolytic cleavage in thin endometrium Cellular and Molecular Life Sciences · 2023 · 9 citations
    20. Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy Research Square (Research Square) · 2020
    21. Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy Research Square (Research Square) · 2020
    22. Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy 2020
    23. β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010 · 314 citations
    24. Comparative secretome analysis of human follicular dermal papilla cells and fibroblasts using shotgun proteomics BMB Reports · 2012 · 44 citations
    25. The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells Stem Cells and Development · 2014 · 42 citations
    26. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    27. Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells Experimental Dermatology · 2012 · 6 citations
    28. Distinct tooth regeneration systems deploy a conserved battery of genes bioRxiv (Cold Spring Harbor Laboratory) · 2020
    29. Prevalence of polycystic ovaries in women with self-reported symptoms of oligomenorrhoea and/or hirsutism: Northern Finland Birth Cohort 1966 Study Human Reproduction · 2004 · 77 citations
    30. Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis Cancer Prevention Research · 2010 · 5 citations