30 citations,
September 2017 in “Clinics in Dermatology” Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
32 citations,
January 2007 in “KARGER eBooks” Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.
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January 2001 in “Cambridge University Press eBooks” Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.
62 citations,
December 2015 in “Clinical Medicine” Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).
1 citations,
November 2011 in “Open access journal of contraception” Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.
14 citations,
January 2008 in “Gynecological Endocrinology” High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
9 citations,
January 2007 in “Gynecological Endocrinology” A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.
5 citations,
January 2009 in “Dermato-endocrinology” ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
66 citations,
November 2001 in “European journal of endocrinology” Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
11 citations,
October 2018 in “Hormone and Metabolic Research” Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
317 citations,
April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
124 citations,
June 2002 in “Best Practice & Research Clinical Endocrinology & Metabolism” Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.
11 citations,
April 2019 in “International Journal of Molecular Sciences” Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.
69 citations,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
4 citations,
January 2018 in “JBRA assisted reproduction” Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
71 citations,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
9 citations,
March 2018 in “International journal of molecular sciences” Allopregnanolone changes gene expression in glioblastoma cells.
3 citations,
March 2020 in “International Journal of Molecular Sciences” Thymosin β4 helps increase hair growth in Cashmere goats.
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1 citations,
November 2023 in “Reproductive biology and endocrinology” Most women with PCOS have insulin resistance, especially those with phenotype B.
45 citations,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
26 citations,
June 2014 in “Fertility and Sterility” Teens with PCOS and a mom with PCOS have higher insulin resistance and lower adiponectin levels, which could signal early metabolic problems.
16 citations,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
4 citations,
November 2017 in “Scientific Reports” The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
378 citations,
September 1998 in “The Journal of Clinical Endocrinology and Metabolism” PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.
October 2023 in “Advancement in yoga and physical therapy” More research is needed before using brown fat to treat polycystic ovary syndrome.
633 citations,
September 1998 in “The Journal of Clinical Endocrinology and Metabolism” PCOS affects a similar percentage of Black and White women in the Southeastern United States.
8 citations,
June 2022 in “Frontiers in bioengineering and biotechnology” A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
39 citations,
January 2012 in “Reproductive Biology and Endocrinology” About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.
25 citations,
December 2008 in “The Journal of Urology” Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.