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    Glossary Insulin-like Growth Factor 2

    protein involved in growth, development, and cell survival

    Insulin-like Growth Factor 2 (IGF-2) is a protein that plays a crucial role in growth and development, particularly during fetal development. It functions similarly to insulin and is involved in cell growth, differentiation, and survival. IGF-2 is also important in tissue regeneration and repair, and its dysregulation has been linked to various conditions, including cancer and growth disorders.

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    1. Association of insulin-like growth factor 2 Apa1 A820G gene (rs680) polymorphism with polycystic ovarian syndrome International journal of reproduction, contraception, obstetrics and gynecology · 2016
    2. l-Ascorbic acid 2-phosphate promotes elongation of hair shafts via the secretion of insulin-like growth factor-1 from dermal papilla cells through phosphatidylinositol 3-kinase 2009 · 34 citations
    3. Regulation of human dermal papilla cell production of insulin-like growth factor binding protein-3 by retinoic acid, glucocorticoids, and insulin-like growth factor-1 Journal of cellular physiology · 1996 · 37 citations
    4. Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells PLoS ONE · 2011 · 39 citations
    5. Insulin-like growth factor-1: roles in androgenetic alopecia Experimental Dermatology · 2014 · 27 citations
    6. Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles International Journal of Molecular Medicine · 2011 · 28 citations
    7. Cashmere growth control in Liaoning cashmere goat by ovarian carcinoma immunoreactive antigen-like protein 2 and decorin genes Asian-Australasian journal of animal sciences · 2018 · 7 citations
    8. The hair growth promoting effect of ascorbic acid 2-phosphate, a long-acting Vitamin C derivative Journal of Dermatological Science · 2006 · 33 citations
    9. Dietary isoflavone increases insulin-like growth factor-I production, thereby promoting hair growth in mice The Journal of Nutritional Biochemistry · 2011 · 29 citations
    10. Promotion of Insulin-Like Growth Factor-I Production by Sensory Neuron Stimulation; Molecular Mechanism(s) and Therapeutic Implications Current medicinal chemistry · 2008 · 23 citations
    11. The Association Between Low (Or Reduced) Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 with Hair Loss in Women. A Case- Control Study in Basrah City of Iraq Zenodo (CERN European Organization for Nuclear Research) · 2026
    12. The Association Between Low (Or Reduced) Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 with Hair Loss in Women. A Case- Control Study in Basrah City of Iraq Zenodo (CERN European Organization for Nuclear Research) · 2026
    13. 730 M2 macrophages promote wound induced hair neogenesis through the production of growth factors 2016
    14. Induction of insulin‐like growth factor‐I by cepharanthine from dermal papilla cells: A novel potential pathway for hair growth stimulation The Journal of Dermatology · 2013 · 13 citations
    15. Synovial membrane mesenchymal stem cell [SM-MSC] induced IGF-1 promote growth factor release in conditioned medium SM-MSC IOP Conference Series Earth and Environmental Science · 2021 · 2 citations
    16. Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet British Journal of Dermatology · 2016 · 93 citations
    17. Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans Growth hormone & IGF research · 2008 · 39 citations
    18. Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells Clinical and Experimental Dermatology · 2017 · 22 citations
    19. Cow placenta extract promotes murine hair growth through enhancing the insulin - like growth factor-1 2011 · 22 citations
    20. Efficacy of 1,550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/β-Catenin in Androgenetic Alopecia Dermatologic Surgery · 2018 · 10 citations
    21. Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2019 · 9 citations
    22. Red Deer Antler Extract Accelerates Hair Growth by Stimulating Expression of Insulin-like Growth Factor I in Full-thickness Wound Healing Rat Model Asian-australasian Journal of Animal Sciences · 2012 · 4 citations
    23. 1049 Novel strategy to promote hair follicle growth and stem cell activation in human male scalp skin: Targeting prolactin receptor with ABS-201 Journal of Investigative Dermatology · 2026
    24. The Association between Low (or Reduced) Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 with Hair Loss in Women. A Case-Control Study in Basrah, Iraq European Journal of Medical and Health Research · 2026
    25. Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil). Endocrinology · 1999 · 43 citations
    26. Role of insulin-like growth factor-1 receptor in female androgenetic alopecia Menoufia Medical Journal · 2020
    27. Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-like Growth Factor 1 1999 · 33 citations
    28. Investigation of Insulin-Like Growth Factor 1 Receptor Expression in Cases of Sacrococcygeal Pilonidal Sinus Medical records-international medical journal · 2023
    29. The localisation and characterisation of insulin-like growth factor-I receptors and the investigation of melatonin receptors on the hair follicles of seasonal and non-seasonal fibre-producing goats 1996 · 26 citations
    30. Visible-to-Near IR Quantum Dot–Based Hypermulticolor High-Content Screening of Herbal Medicines for the Efficacy Monitoring of Hair Growth Promotion and Hair Loss Inhibition SLAS discovery · 2012 · 14 citations