December 2022 in “Archives of Dermatological Research” This study found that topical cetirizine increased hair shaft thickness and improved clinical outcomes from the patients' perspective in female androgenetic alopecia compared to minoxidil alone, with similar side effect profiles.
10 citations
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October 2021 in “Animal nutrition” This study found that dietary pyridoxine increased hair follicle density in Rex rabbits by activating PI3K/Akt, Wnt, and Notch signaling pathways, which may promote hair growth and delay telogen onset.
2 citations
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May 2023 in “Journal of Advanced Research” In this study, researchers identified two genetic mutations associated with producing finer and denser wool in fine-wool sheep, involving the genes KRT74 and EDAR, which may guide future breeding efforts to enhance wool quality.
1 citations
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December 2023 in “Animals” In this study, researchers observed that the skin quality and hair follicle development of Rex rabbits improved when slaughtered in winter compared to summer, with findings suggesting seasonal regulation via multiple signaling pathways affecting fur characteristics.
January 2026 in “Journal of Ethnopharmacology” This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.
This study observed that a combination of sinapic acid and glabridin from Zhimo herbal extract improved hair growth and reduced oxidative stress in a DHT-induced model of androgenetic alopecia in mice by preventing ferroptosis and stabilizing β-Catenin, offering potential application for AGA treatment.
June 2025 in “Frontiers in Bioengineering and Biotechnology” In this study, the researchers observed that a recombinant human collagen complex with nicotinamide promoted hair growth in rat models, increased hair follicle stem cell survival, and enhanced key protein expression, suggesting potential benefits for hair health and loss prevention.
May 2025 in “International Journal of Molecular Sciences” In a mouse study, Fr2 from Platycladus orientalis L. significantly enhanced hair growth, suggesting its potential as a natural therapeutic agent for hair regeneration.
April 2024 in “Journal of Investigative Dermatology” This study identified three new genetic loci linked to sweat gland density in a GWAS involving 6,210 Han Chinese individuals, highlighting potential targets for understanding conditions like anhidrosis and hyperhidrosis and emphasizing the use of quantitative traits in genetic dermatology research.
November 2023 in “International Journal of Cosmetic Science” This study found that a wheat polar lipid complex supplement significantly reduced hair loss and improved hair growth and volume in women experiencing acute hair shedding, including postmenopausal women.
August 2023 in “Stem Cell Research & Therapy” This study found that cell-free fat extract (CEFFE) enhanced hair growth in mice with androgenetic alopecia by increasing hair follicle density and promoting proliferation while regulating the DHT/AR pathway.
July 2025 in “Highlights in Science Engineering and Technology” In this study, researchers found that nanomaterials designed for plastic surgery applications show promising results, including a 95% dynamic wrinkle filling rate and enhanced hair density by 41%; however, challenges like potential long-term safety issues and high production costs must be addressed.
1 citations
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January 2022 in “Medical Science” This study found that patients with Alopecia Areata, particularly those with severe forms, exhibited higher triglycerides, cholesterol, and low-density lipoproteins, suggesting increased cardiovascular risk factors.
1 citations
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July 2023 in “Archives of dermatological research” This study found that both 0.01% and 0.03% bimatoprost gel and 2% minoxidil gel significantly improved eyebrow density in individuals with hypotrichosis, with no significant difference between the treatments, although the highest bimatoprost concentration showed a more favorable response.
13 citations
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December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
15 citations
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January 2020 in “BioMed Research International” In this study of patients with androgenetic alopecia, botulinum toxin type A was found to significantly increase hair counts and improve hair density and coverage, with enhanced results observed when combined with oral finasteride, revealing a safe and effective treatment approach without adverse effects.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.
September 2019 in “Journal of Investigative Dermatology” This study demonstrated that an RO formulation significantly improved neck wrinkles after 8 weeks of application, compared to a placebo, in Japanese female subjects.
This study found that somatosensory axons innervating Merkel cells in adult mouse skin exhibit significant plasticity, influenced by epithelial and neural factors, indicating a complex interaction in maintaining homeostasis.
24 citations
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March 2008 in “Neuroscience Research” This study revealed the complex three-dimensional innervation of touch domes in cat forepaw skin, highlighting the extensive branching and unmyelinated endings associated with Merkel cell–axon complexes.
March 2025 in “Frontiers in Cell and Developmental Biology” This study reviewed how neuropeptides and cutaneous innervation play crucial roles in the process of wound healing, suggesting they significantly influence inflammation and tissue repair phases.
9 citations
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July 2018 in “European journal of dermatology/EJD. European journal of dermatology” This study provides evidence that long-term deregulation of the circadian rhythm in humans affects the regenerative properties of skin and hair precursor cells by altering clock pathway protein expression.
January 2025 in “International Journal of Cosmetic Science” This study found that citric acid treatment can significantly improve the structural integrity and mechanical properties of chemically treated hair, reducing damage by increasing keratin crosslinking density and decreasing crystallized calcium soaps, with varying effectiveness depending on the type of chemical treatment.
January 2022 in “Sustainable development goals series” The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.
This study in adult mice found that somatosensory axons innervating Merkel cells in the skin are highly plastic, with significant remodeling in response to epithelial turnover, and that Merkel cells play a role in limiting axonal branching and promoting their maturation.
This study observed a high degree of plasticity in somatosensory axons innervating Merkel cells in mouse skin, finding that both axons and Merkel cells underwent dynamic remodeling, with their interactions influencing axonal branching and maturation.
2 citations
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January 2014 in “Hair therapy & transplantation” This study found that combining oral chelated Zinc with 5% minoxidil solution improved hair density and hair shaft diameter in women with female pattern hair loss, without reported side effects.
February 2026 in “International Journal of Nanomedicine” This study demonstrated that engineered exosomes carrying EGF and FGF restored hair density and follicle integrity in an androgenetic alopecia mouse model by reactivating hair follicle growth factors, offering a novel therapeutic approach without immunogenic reactions or systemic toxicity.
In this study, researchers observed a high degree of plasticity in somatosensory axons innervating Merkel cells in adult mouse skin, with both epithelial and neural components exhibiting dynamic remodeling, highlighting intricate epithelial-neural interactions in maintaining homeostasis.
In this study, researchers observed a high degree of plasticity in somatosensory axons innervating Merkel cells in adult mouse skin, revealing that both epithelial-neural crosstalk and intrinsic neural mechanisms contribute to axonal patterning and remodeling during epithelial homeostasis.