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Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

CBD may improve skin and hair health, but its effective use and safety need more research.

Mesenchymal stem cells could help treat radiation-induced bladder damage but more research is needed to overcome current limitations.

Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.

Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.

Finasteride helps female-pattern hair loss.

Aged individuals heal wounds less effectively due to specific immune cell issues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.