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This research notes that biologics and small molecules are effective for treating nail psoriasis and alopecia areata, albeit with precautions for adverse events, but no clinical trials have been published for their use in treating nail lichen planus and atopic dermatitis.

This review examines targeting the JAK-STAT pathway in inflammatory skin diseases, highlighting existing JAK inhibitors and potential developments, but presents no new experimental or clinical results.

This review examines the role of cell adhesion molecules in the pathogenesis of various inflammatory and neoplastic skin diseases, suggesting their potential utility in diagnosis and treatment without presenting new clinical results.

This study explored new molecular structures as potential COVID-19 treatments, identifying a compound called Hit15 that inhibited viral infection in lab settings and reduced inflammation markers in human neutrophils, suggesting further development is warranted.

This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.

This study suggests that Cepharanthine, a monomer in traditional Chinese medicine, may help treat COVID-19 by affecting multiple signaling pathways, and that TNF and IL-17 inhibitors used in rheumatoid arthritis, ankylosing spondylitis, and gouty arthritis might also be beneficial.

This review explores the molecular mechanisms through which NGF may enhance burn wound healing by reducing healing time and improving scar quality, but it presents no new clinical results.

This review discusses the bidirectional interactions between human mast cells and CD8 T cells in the skin, particularly in the context of disorders like psoriasis, atopic dermatitis, and vitiligo, and reports no new findings.

This study explored the molecular mechanisms by which Polygonum multiflorum may treat androgenic alopecia, suggesting it influences cell apoptosis and inflammation through specific pathways, with potential application value pending further testing.

This study identified shared gene expression changes and immune cell infiltration patterns that may contribute to hair loss in alopecia areata and cutaneous lupus erythematosus, but also highlighted factors that might preserve hair in psoriasis patients.

This study found that SM04755, a novel topical drug, inhibited inflammation, keratinocyte proliferation, and fibrosis in vitro and improved skin health in a mouse model of psoriasis, indicating potential as a topical psoriasis treatment.

This study suggests that polygonum multiflorum may treat androgenic alopecia by mediating the PI3K/Akt pathway to regulate apoptosis, inhibit inflammation and oxidative stress, and induce melanin production.

This study concluded that shikonin, a small molecule derived from herbal extract, promotes wound healing and reduces inflammation in mice by activating the PI3K/Akt signaling pathway.

This review suggests that curcumin and piperine may offer a promising multi-target therapeutic approach for alopecia by simultaneously modulating androgenic and inflammatory pathways, though experimental and clinical validation are necessary to confirm their efficacy.

In this review, researchers explored the potential of a curcumin–piperine combination in alopecia management through computational analyses, highlighting its capacity to modulate multiple pathways involved in hair follicle homeostasis, although further experimental and clinical validation is necessary to confirm its efficacy.

This review found that adding immune checkpoint inhibitors to cancer treatment regimens likely increases the incidence of specific drug-related skin toxicities in adult Asian patients, highlighting the need for careful monitoring and management strategies.

This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.

This case report highlights that asymptomatic domestic cats can transmit Microsporum canis, leading to tinea capitis in humans, as seen in a four-year-old girl in the study.

This study suggests that Hejie Shengfa Decoction may help treat alopecia areata by influencing immune and inflammatory pathways, regulating apoptosis, and enhancing the follicular microenvironment.

In this animal study, researchers found that local administration of mesenchymal stem cell therapy improved hair regrowth and reduced local inflammatory cytokines in mice with Alopecia Areata, although systemic cytokine levels were unchanged.

This study found that the Qing Cuo Formula significantly reduced serum androgen and inflammatory cytokine levels in hamsters with damp-heat acne and identified potential molecular mechanisms and active compounds involved.

JAK inhibitors improve hair growth in alopecia areata, especially in patchy types.

This review compiled evidence suggesting that flavonoids may promote skin wound healing due to their anti-inflammatory, angiogenesis, re-epithelialization, and antioxidant properties, while also discussing current limitations and future prospects for these compounds as wound-healing agents.

This review highlights the role of plant-derived organic selenium compounds, noting their high bioavailability and low toxicity, and provides a comprehensive overview of selenium's uptake in plants and metabolism in humans, offering a theoretical basis for future nutritional research.

This review discusses the dermatological applications and potential health benefits of Epigallocatechin-gallate (EGCG) from green tea, but provides no new clinical findings.

In this study, OEA was found to significantly enhance sebaceous lipogenesis and potentially reduce inflammation in human sebocytes, suggesting it as a promising candidate for treating skin dryness.

This study reviews advances in targeted therapies for moderate-severe dermatological conditions like plaque psoriasis and atopic dermatitis, reporting on newly approved treatments and highlighting the need for further innovations in managing rare inflammatory skin diseases through emerging laboratory techniques and trials.

This study identified overexpression of certain immune-related genes and underexpression of genes in specific signaling pathways in premature androgenetic alopecia, suggesting potential new therapeutic targets.

In this study, rice bran mineral extract increased expression of anagen-related proteins and decreased inflammatory markers in human dermal papilla cells, suggesting potential for hair growth enhancement and prevention of hair loss.

In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.