research Frontal fibrosing alopecia: Histopathological and immunohistochemical study of the inflammatory infiltrate and the sebaceous gland receptors
Frontal fibrosing alopecia may be caused by an autoimmune reaction and hormonal imbalance.
Search
for
Sort by
Research
30 / 1000+ results
research Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level
This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.
research 0994 Inflammatory infiltrate precedes collapse of the immune privilege in human alopecia areata
research Pro-inflammatory Vδ1+T-cells infiltrates are present in and around the hair bulbs of non-lesional and lesional alopecia areata hair follicles
This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.
research Immunohistochemical analysis of T-cell subsets in the inflammatory infiltrates of alopecia areata and its comparison with androgenetic alopecia
This study found that peribulbar lymphocytic infiltration can effectively differentiate between alopecia areata and androgenetic alopecia using T-cell infiltration patterns in skin tissue.
research Alopecia in Rhesus macaques correlates with immunophenotypic alterations in dermal inflammatory infiltrates consistent with hypersensitivity etiology
This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.
research Inflammatory perifollicular fibrosis and alopecia
This article discusses inflammatory perifollicular fibrosis and alopecia but provides no new research findings.
research Immunohistochemical assessment of SOX10 and its relation to the immune cellular infiltrate in alopecia areata follicles
In this observational study, SOX10 was expressed in 53 out of 81 examined hair follicles in patients with alopecia areata and showed a significant positive relation with the perifollicular lymphocytic infiltrate, suggesting that melanocytes may play a role in the disease's autoimmune pathogenesis.
research The Inflammatory Aspect of Male and Female Pattern Hair Loss
This perspective highlights the role of inflammation in male and female pattern hair loss and its implications for developing future therapeutic options.
research Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia
This study reports that two mouse models of scarring alopecia exhibit similar patterns of hair loss progression despite histological differences in inflammatory cell localization and MHC class I expression.
research The Inflammatory Aspect of Male and Female Pattern Hair Loss
This perspective highlights evidence suggesting inflammation plays a significant role in male and female pattern hair loss, indicating that targeting inflammatory pathways may improve future therapeutic options.
research Androgenic pattern presentation of scarring and inflammatory alopecia
This article provides no abstract or new research findings on the androgenic pattern presentation of scarring and inflammatory alopecia.
research Histopathological characterization of inflammatory interparietal involvement in frontal fibrosing alopecia
This article questions whether frontal fibrosing alopecia and fibrosing androgeneic patterned hair loss are overlapping conditions or stages of the same process, calling for further research to clarify their underlying factors.
research A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib
This article discusses the cutaneous side effects of erlotinib, an EGFR inhibitor, in a patient with non-small cell lung cancer, reporting nonscarring alopecia and indicative scalp biopsy findings.
research Oral syphilis: report of three cases and characterization of the inflammatory cells
This study highlights the importance of recognizing oral lesions in diagnosing syphilis, as illustrated by three reported cases.
research Fucoidan treatment reverses hair loss and inhibits inflammatory responses in a mouse model of androgenetic alopecia
Fucoidan may help regrow hair and reduce inflammation in hair loss.
research 0041 Comparative multi-omics highlights inflammatory monocyte-derived dendritic cells as key mediators of UVB-induced photosensitivity
Monocyte-derived dendritic cells play a key role in UVB-induced skin sensitivity and inflammation.
research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes
This study found that mechlorethamine restored hair growth in mice with alopecia-areata-like disease by eliminating infiltrated lymphocytes and inhibiting certain pro-inflammatory cytokines in treated skin areas.
research CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment
In this study, researchers found that hair follicle stem cells activate an immune-modulatory program during wound healing, promoting Treg cell expansion and aiding skin repair, while deleting certain immune components impaired healing and increased inflammation in a mouse model.
research Fibrosing Alopecia in a Pattern Distribution
This study reports that some patients with androgenetic alopecia may also exhibit clinical and histological features of inflammation and fibrosis, similar to those found in lichen planopilaris.
research Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia
This study found that anti-TNF therapy-induced alopecia exhibits distinct clinical and histopathological features and can mimic psoriatic alopecia and alopecia areata, with some patients improving with topical treatment.
research The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study
This study reports that plasma rich in growth factors appeared to improve hair follicle regeneration and patient satisfaction in individuals with androgenetic alopecia, though further trials are needed.
research Current applications of high-frequency ultrasonography in dermatology
This review highlights the increasing clinical applications of high-frequency ultrasonography in dermatology, particularly for assessing the depth of skin tumors and monitoring inflammatory skin diseases, but reports no new clinical results.
research Erosive pustular dermatosis of the scalp following topical methylaminolaevulinate photodynamic therapy
This case study identified erosive pustular dermatosis of the scalp following methylaminolaevulinate photodynamic therapy, noting improvement with steroid treatment and partial resolution of atrophy after three months.
research The Transverse Anatomy of Androgenic Alopecia
This study found decreased hair density and altered follicular architecture in the balding frontal scalp of patients with androgenic alopecia, with increased vellus hairs noted.
research The efficacy of laser-assisted hair removal in the treatment of acne keloidalis nuchae; a pilot study
This study found that long pulsed Nd-YAG laser treatment significantly improved acne keloidalis nuchae by reducing inflammation and hair follicles, with early intervention yielding the best results.
research Tinea capitis mimicking dissecting cellulitis of the scalp: a histopathologic pitfall when evaluating alopecia in the post‐pubertal patient
A fungal infection can look like a different scalp condition in teens, leading to wrong treatment until proper tests are done.
research Radioprotection of Lung Tissue by Soy Isoflavones
In this animal study, soy isoflavones were found to protect lung tissue from the adverse effects of radiation, such as skin injury, inflammation, and fibrosis, suggesting a potential radioprotective benefit.
research Cutaneous wound healing: canine allogeneic ASC therapy
This study found that treating acute and chronic canine skin wounds with adipose-derived mesenchymal stem cells significantly improved healing and reduced inflammation, suggesting potential benefits for human wound care.
research Central Centrifugal Cicatricial Alopecia Presenting with Irregular Patchy Alopecia on the Lateral and Posterior Scalp
This study identified a new variety of central centrifugal cicatricial alopecia that includes patchy hair loss on the lateral and posterior scalp in African-American women, which could be misdiagnosed as traction alopecia without dermatoscopy and pathology.