Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the immune-mediated mechanism behind alopecia areata, highlighting similarities between the condition in humans and animals, and reports no new clinical results.

This study found that in a mouse model, betamethasone dipropionate reduced epidermal thickness while fish oil unexpectedly increased it, validating optical coherence tomography as an effective measurement tool.

This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.

This case report suggests that frequent application of diphenylcyclopropenone 2% solution to the scalp for alopecia areata may lead to scalp angioedema.

This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.

This review discusses the multifactorial pathogenesis of hidradenitis suppurativa and calls for more diverse, standardized clinical trials to improve treatment and understanding of dietary influences, reporting no new results.

This case report describes a patient with psoriasis who developed alopecia with unique histological features after anti-TNF therapy, suggesting that such effects may require considering treatment suspension for severe cases.

This animal study found that berberine may alleviate benign prostatic hyperplasia by reducing inflammation and oxidative stress through inhibition of the NF-κB signaling pathway.

In this review, researchers detail how immunosenescence and chronic neuroinflammation contribute to Parkinson's disease progression, exploring potential therapeutic strategies targeting this axis, such as senolytic agents and immune rejuvenation, while highlighting associated challenges and future research needs.

This article traces the historical development of hidradenitis suppurativa's naming and classification, noting that naming disagreements persist despite extensive research.

In this study, reflectance confocal microscopy was shown to provide early insights into sub-clinical treatment progress in patients with androgenetic alopecia, potentially offering advantages over global photography.

This study found that women with late onset acne have fewer comedones and acne lesions compared to those with early onset, despite no differences in P. acnes density or sebum secretion.

This study found that overexpression of PKCα in mouse epidermis increases expression of specific proinflammatory mediators and induces inflammation but does not significantly affect epidermal differentiation, proliferation, or tumor promotion with TPA.

Hair transplantation can lead to rare scalp complications, requiring careful follow-up and treatment.

This study found that macrophages near hair follicles contribute to the activation of skin epithelial stem cells in mice, suggesting a novel role for macrophages in regulating hair growth.

This introduction highlights the impact of acne vulgaris on quality of life and the complexity of selecting effective treatments, but it presents no new clinical results.

This study found that children with intracranial injuries had significantly lower odds of achieving satisfactory early academic performance compared to those without head injuries.

This review discusses the characteristics and challenges in treating Cronkhite–Canada syndrome but reports no new clinical findings, emphasizing the need for better understanding and uniform treatment approaches.

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

In this study, UDCA treatment reduced inflammation, oxidative stress, and cartilage damage in rats with experimentally induced rheumatoid arthritis, suggesting potential anti-rheumatoid arthritis properties.

In this study, researchers observed that hidradenitis suppurativa lesions were associated with reduced collagen and elastin, and increased neovascularization in areas with chronic inflammation.

A man with both skin lesions and lung cancer improved quickly with chemotherapy, suggesting the skin condition might be a reaction to immune system injury.

In this study, researchers found that K17−/− mice suffered more severe hair follicle damage but showed reduced epidermal inflammation after ionizing radiation, with K17's absence leading to aberrant cell cycle progression due to altered p53 genome binding and reduced B-Myb degradation.

This study found that Zhuangyao Jianshen pill significantly improved prostate health in testosterone-induced benign prostatic hyperplasia in castrated rats by modulating sex hormones and reducing inflammation and oxidative stress.

This study found that hospitalized pediatric COVID-19 patients frequently display skin, mucosal, and nail manifestations, particularly periorbital erythema and edema, and the authors suggest COVID-19 be considered among childhood viral exanthem rashes.

This study found that a chitosan, chondroitin sulfate, and hyaluronic acid scaffold improved wound healing in rats by promoting immune-stromal interactions, reducing inflammation, and supporting tissue regeneration with ~91% wound closure by day 17 compared to ~63% in controls.

In this study, researchers used a mouse model to identify an adipocyte-to-fibroblast conversion pathway that promotes mast-cell recruitment and dermal fibrosis in atopic dermatitis, suggesting a potential therapeutic approach to block this process and reduce inflammation and fibrosis.

In this study, PA-011 extract was reported to promote hair growth and alleviate alopecia areata symptoms in mice by reducing skin inflammation and modulating skin microbiota.

This study provides a detailed analysis of cell subpopulations in a mouse model of wound-induced hair follicle regeneration, revealing specific cellular dynamics and heterogeneity that may influence hair follicle neogenesis.

The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.