43 citations
,
February 2019 in “International immunology” This review examines the role of regulatory T cells in skin immune disorders, highlighting their unique functions in conditions like scleroderma, alopecia areata, and psoriasis, without reporting new clinical results.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
194 citations
,
March 2003 in “American Journal of Pathology” This study found that psychoemotional stress disrupts hair growth in mice by terminating anagen and suggests a potential pathway for pharmacological management of stress-related hair loss in humans.
April 2025 in “Egyptian journal of Immunology” In this study, researchers reported significantly higher serum calprotectin levels in alopecia areata patients compared to controls and that these levels were associated with the disease's severity, type, duration, and nail involvement, suggesting calprotectin as a potential marker for inflammation in these patients.
August 2023 in “Journal of Knowledge Learning and Science Technology ISSN 2959-6386 (online)” This review discusses the use of single-cell RNA sequencing and spatial transcriptomics to enhance understanding of the pathogenesis and targeted therapies for chronic inflammatory skin conditions, highlighting technology advancements and the need for cost reduction and standardization.
105 citations
,
August 2010 in “Pharmacology & therapeutics” This article explores the potential of formyl-peptide receptor 2 agonists as innovative anti-inflammatory drugs, highlighting their ability to mimic the body's natural inflammation response, but it presents no new clinical findings.
January 2024 in “Frontiers in immunology” This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.
60 citations
,
September 2013 in “Alimentary Pharmacology & Therapeutics” This review discusses the dermatological adverse events from immunosuppressive and anti-TNF therapy in IBD, finding increased risks of non-melanoma skin cancer and other skin conditions, and recommends regular cancer screening.
59 citations
,
June 2022 in “Frontiers in medicine” This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.
January 2023 in “Bio web of conferences/BIO web of conferences” This study identified specific dermoscopic features for differentiating rosacea, seborrheic dermatitis, contact dermatitis, and atopic dermatitis, suggesting dermoscope's value in diagnosing facial erythema with atypical presentations.
January 2025 in “Medical Research Archives” This review discusses various applications of low level laser therapy and argues for a holistic evaluation of patients but reports no new clinical findings.
21 citations
,
November 2022 in “Frontiers in immunology” This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.
April 2024 in “Cell death and differentiation” This study discusses how different modes of regulated cell death in keratinocytes affect skin stem cell niches, and their role in skin inflammation, injury repair, and cancer, based on findings from human dermatological conditions and experimental mouse models.
May 2023 in “Buletin Veteriner Udayana” This study found that dogs with dermatitis exhibited specific histological skin changes, such as hyperkeratosis and inflammatory cell infiltration, and showed increased leukocyte counts compared to non-dermatitis dogs.
January 2022 in “Skin appendage disorders” This case report describes a unique occurrence of alopecia totalis resulting in pigmented hair growth over superficial scalp veins in an adult female using augmented betamethasone dipropionate ointment.
March 2017 in “The American Journal of Cosmetic Surgery” This case report suggests that transplanted hair follicles may be more resistant to alopecia areata than native hair, potentially offering new insights into the condition's pathophysiology and treatment options.
16 citations
,
December 2012 in “The Clinical Journal of Pain” This study found that trichodynia is associated with both peripheral and central sensitization, potentially linked to hair cycle abnormalities and chronic pain through proinflammatory agents.
2 citations
,
August 2020 in “Journal of Cosmetic Dermatology” This study found that in patients with alopecia areata, serum granulysin levels decreased significantly after treatment with tofacitinib and correlated with reduced disease severity, suggesting serum granulysin as an indicator of immunological activity and response to therapy.
September 2025 in “Ankara Universitesi Eczacilik Fakultesi Dergisi” This study analyzed the therapeutic potential of various plant species for alopecia areata treatment, highlighting their possible benefits due to anti-inflammatory and immunomodulatory properties, though more research is needed to fully understand the mechanisms involved.
47 citations
,
December 2019 in “Frontiers in immunology” This study identified a novel G207E STING mutation associated with severe inflammatory symptoms and suggested that common polymorphisms in TMEM173 and IFIH1 may modify the phenotype in affected individuals.
39 citations
,
May 2011 in “Human Immunology” This review discusses findings from genetic studies on acne, highlighting progress in understanding its molecular pathogenesis without reporting new clinical results.
34 citations
,
March 2015 in “Clinical and Experimental Dermatology” This study observed that patients with pemphigus have a higher incidence of hypothyroidism, inflammatory bowel disease, and diabetes compared to the general population.
24 citations
,
August 2017 in “Prostaglandins & Other Lipid Mediators” This review discusses the potential roles of prostaglandin D2 and its receptor CRTH2 in various diseases beyond allergies and asthma and reports no new clinical results.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” This review discusses the pathogenesis of common sebaceous gland diseases and their molecular pathways, but it reports no new clinical findings.
4 citations
,
March 1989 in “The BMJ” Naproxen is not the cause of hair loss in a child; it's due to a toxic event with expected hair regrowth.
2 citations
,
June 2023 in “PeerJ” This review discusses how chronic inflammation can lead to persistent stem cell activation and DNA damage, ultimately promoting cancer development and metastasis, but reports no new results.
research Acne
2 citations
,
May 2011 in “Harper's Textbook of Pediatric Dermatology” Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
1 citations
,
August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that a novel gain-of-function mutation in TMEM173, combined with polymorphisms in TMEM173 and IFIH1, results in a distinct clinical phenotype with features of SAVI, including alopecia and photosensitivity.
February 2026 in “Eduvest - Journal Of Universal Studies” This review discusses the molecular mechanisms and therapeutic effectiveness of Janus Kinase Inhibitors for inflammatory skin diseases, suggesting these inhibitors have a rapid onset and favorable safety profile compared to conventional treatments.
February 2026 in “ImmunoTargets and Therapy” This study found that tumor immunotherapy, while effective against solid tumors, can disrupt the immune balance in hair follicles, causing follicular toxicity and alopecia, highlighting the need for targeted interventions to manage these adverse effects.