Search

for
Search:

GlossaryInflammatory Pathways

molecular signals triggering the body's response to harmful stimuli

Inflammatory pathways, also known as inflammatory signaling pathways, are a series of molecular signals and reactions that the body uses to respond to harmful stimuli, such as pathogens, damaged cells, or irritants. These pathways involve various cells and proteins, including cytokines and chemokines, which work together to initiate and regulate inflammation, ultimately aiming to protect and heal the body. Understanding these pathways is crucial for developing treatments for conditions like alopecia, where inflammation can play a significant role in hair loss.

Related Terms

Sort by

Research

30 / 1000+ results

ROBO4 Deletion Ameliorates PAF-Mediated Skin Inflammation by Regulating the mRNA Translation Efficiency of LPCAT1/LPCAT2 and the Expression of PAF Receptor

research ROBO4 Deletion Ameliorates PAF-Mediated Skin Inflammation by Regulating the mRNA Translation Efficiency of LPCAT1/LPCAT2 and the Expression of PAF Receptor

6 citations, January 2020 in “International journal of biological sciences”

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

research Eupafolin Nanoparticles Protect HaCaT Keratinocytes from Particulate Matter-Induced Inflammation and Oxidative Stress

43 citations, August 2016 in “International Journal of Nanomedicine”

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele

1 citations, August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

research Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

14 citations, June 2018 in “Frontiers in pharmacology”

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

Chronic Inflammatory Diseases Stimulated by Current Lifestyle: How Diet, Stress Levels, and Medication Prevent Our Body from Recovering

research Chronic Inflammatory Diseases Stimulated by Current Lifestyle: How Diet, Stress Levels, and Medication Prevent Our Body from Recovering

119 citations, January 2012 in “Nutrition & Metabolism”

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Synergistic Phytochemical and Pharmacological Actions of Hair Rise Microemulsion: A Novel Herbal Formulation for Androgenetic Alopecia and Hair Growth Stimulation

research Synergistic Phytochemical and Pharmacological Actions of Hair Rise Microemulsion: A Novel Herbal Formulation for Androgenetic Alopecia and Hair Growth Stimulation

October 2024 in “Plants”

Hair RiseTM microemulsion effectively promotes hair growth and treats hair loss better than standard treatments.

research Wound Healing: A Cellular Perspective

1160 citations, November 2018 in “Physiological Reviews”

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

research A Bibliometric Study of Scientific Literature in Scopus on Botanicals for Treatment of Androgenetic Alopecia

15 citations, November 2015 in “Journal of Cosmetic Dermatology”

Botanicals like green tea extract show potential for hair growth, but more research is needed.

research Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys Cahirinus

24 citations, May 2019 in “PLOS ONE”

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

research Platelet Lysate Promotes Hair Growth: In Vitro and In Vivo Mechanism and Randomized, Controlled Trial

2 citations, March 2023 in “Biomedicine & pharmacotherapy”

Platelet lysate effectively promotes hair growth and improves hair thickness in people with androgenetic alopecia.

research Design and Characterization of Baricitinib Incorporated PLA 3D Printed Pills by Fused Deposition Modeling for Treating Alopecia Areata

2 citations, April 2023 in “Polymers”

The study created 3D-printed pills that effectively release a hair loss treatment drug over 24 hours.

research Industry Updates from the Field of Stem Cell Research and Regenerative Medicine in December 2019

1 citations, February 2020 in “Regenerative Medicine”

Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.

research DNA Microarray and Bioinformatic Analysis Reveals the Potential of Whale Oil in Enhancing Hair Growth in a C57BL/6 Mice Dorsal Skin Model

May 2024 in “Genes”

Whale oil significantly promotes hair growth and may be a safe, effective alternative to minoxidil.

research Case Report: A Study of the Clinical Characteristics and Genetic Variants of Post-Finasteride Syndrome Patients

September 2022 in “Translational Andrology and Urology”

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

research Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach

3 citations, March 2021 in “Metabolites”

Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.

research Characterization of Novel TMEM173 Mutation Causing a Lupus- and SAVI-Like Phenotype, Modified by Polymorphisms in TMEM173 and IFIH1

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

research Mild Oxidative Stress Protects Against Chemotherapy-Induced Hair Loss

2 citations, January 2023 in “Frontiers in Oncology”

Mild oxidative stress can prevent hair loss from chemotherapy.

research The Acne-Treatment Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil In Vitro and In Vivo

August 2021 in “Research Square (Research Square)”

Borneol Essential Oil could be a natural and safe acne treatment.

research Design of an In Vitro Skin 3D Model Mimicking a Disruption of the Barrier Function

September 2017 in “Journal of Investigative Dermatology”

Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.

research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

47 citations, December 2019 in “Frontiers in immunology”

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes

research Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes

70 citations, February 2019 in “The journal of immunology/The Journal of immunology”

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Unlocking the Potential of the Secretome in Hair Growth Enhancement

research Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies

October 2024 in “Sci”

Nanoformulations improve luteolin's effectiveness as a cancer treatment.

research Pathways to Inflammation: Acne Pathophysiology

68 citations, May 2011 in “European Journal of Dermatology”

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation

18 citations, November 2020 in “Frontiers in Cell and Developmental Biology”

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

research Effects of Natural Products on Skin Inflammation Caused by Abnormal Hormones Secreted by the Adrenal Gland

2 citations, May 2023 in “Frontiers in Pharmacology”

Natural products may help treat skin inflammation from abnormal adrenal hormones.

research C-Reactive Protein Promotes Adhesion of Monocytes to Endothelial Cells via NADPH Oxidase-Mediated Oxidative Stress

24 citations, January 2012 in “Journal of Cellular Biochemistry”

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.

research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling

9 citations, May 2012 in “PLOS ONE”

ILK is essential for skin development, pigmentation, and healing.