February 2026 in “Figshare” This study found that a newly developed biocompatible hydrogel, responsive to reactive oxygen species, enabled targeted delivery of miR-665, significantly promoting hair regeneration and reducing T-cell infiltration in a mouse model of alopecia areata, suggesting a promising strategy for treating this condition.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
January 2026 in “Biomacromolecules” This study reports that a novel nanolipogel with moderate rigidity (NLG-2.5) enhances transdermal delivery of fucosterol, displaying superior permeability, targeting hair follicles, and promoting hair growth in androgenetic alopecia model mice by inhibiting inflammation and androgen pathways and promoting angiogenesis.
January 2026 in “Journal of Investigative Dermatology” Female-pattern hair loss may involve an autoimmune-like process, suggesting new treatment options.
December 2025 in “Advanced Healthcare Materials” In this study, a new topical formulation containing amine-activated carboxymethyl chitosan and hydrolyzed extracellular matrix showed promising results in a mouse model by reducing oxidative stress, inflammation, and promoting hair regeneration, potentially offering an alternative treatment for inflammatory hair loss.
November 2025 in “Preprints.org” In a rodent study, researchers found that oral phenytoin and spironolactone significantly mitigated 5-fluorouracil-induced hair loss and oxidative stress, suggesting potential therapeutic benefits for chemotherapy-induced alopecia and enhanced recovery.
November 2025 in “The Journal of Immunology” This study found that CD80 expression in wound-activated hair follicle stem cells induces Foxp3 expression in effector T cells, facilitating wound repair by converting them into regulatory T cells.
October 2025 in “Frontiers in Immunology” This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.
August 2025 in “Frontiers in Pharmacology” In this study, PA-011, a traditional Chinese medicine extract, was shown to improve hair growth in alopecia areata model mice by reducing skin inflammation and altering skin microbiota, indicating its potential therapeutic role for this condition.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, PA-011 extract was reported to promote hair growth and alleviate alopecia areata symptoms in mice by reducing skin inflammation and modulating skin microbiota.
June 2025 in “Academic Medical Journal” This study suggests elevated homocysteine levels may serve as a biomarker for disease severity and vascular risk in cutaneous lupus erythematosus, indicating potential therapeutic benefits from B-vitamin supplementation and lifestyle changes.
April 2025 in “Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )” In this study, researchers observed that Cuscuta reflexa extract mitigated inflammation and oxidative stress in testosterone-induced benign prostatic hypertrophy in Wistar rats, suggesting its potential as an adjunctive therapy for BPH.
March 2025 in “Wound Repair and Regeneration” In a study using mouse models, researchers developed a gelatin methacryloyl scaffold with calcium-doped silica nanoparticles loaded with deferoxamine, which significantly improved skin flap survival and hair follicle growth, suggesting potential clinical applications in tissue regeneration.
January 2025 in “Journal of Carcinogenesis” This review highlights the potential of anti-inflammatory therapies to reduce major adverse cardiac events in patients with ischemic heart disease, emphasizing that such treatments can be effective even without traditional lipid-lowering strategies.
December 2024 in “Medicina” This study investigated the presence of Helicobacter pylori and Chlamydia trachomatis in women with PCOS, finding no significant association between these infections and PCOS, while also reporting higher inflammation markers and related health issues in the PCOS group compared to controls.
December 2024 in “ACS Applied Materials & Interfaces” In this study, dynamic hyaluronic acid hydrogels with properties like injectability and controlled degradation were developed to enhance healing and remodeling of diabetic wounds, achieving effects such as inflammation reduction, increased angiogenesis, and neovascularization, leading to complete wound healing.
September 2023 in “Research Square (Research Square)” This study found that TNC + fibroblasts are crucial in neuro-immune interactions in various skin diseases, particularly inflammation and tumors, by engaging extensively with immune cells and overexpressing inflammatory genes, suggesting their significant role in skin abnormalities.
July 2023 in “Stem Cells Translational Medicine” This review discusses the roles of mesenchymal stem cells in wound healing, particularly their interactions with immune cells, and highlights the potential and current limitations of MSC-based therapies for tissue regeneration.
April 2023 in “Journal of Investigative Dermatology” This study found variation in erythema induction across skin types, suggesting different SSR dose responses and highlighting a potential model for tailoring anti-inflammatory treatments.
October 2022 in “Frontiers in Cell and Developmental Biology” Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
November 2020 in “Journal of The American Academy of Dermatology” This study examined dermoscopic features in African-American women with different types of alopecia and found that a perifollicular pink blush, potentially indicating inflammation, was common, particularly resolved with anti-inflammatory treatment, suggesting dermoscopy could aid in management.
April 2018 in “Journal of Investigative Dermatology” This study suggests that mechanical tension significantly impacts lymphocyte function, and that a complete lymphocyte population is essential for effective wound healing and reducing inflammation.
September 2017 in “Journal of Investigative Dermatology” This study found that infrared thermography might be a useful non-invasive tool to help diagnose frontal fibrosing alopecia by identifying active phases of the disease.
April 2017 in “Journal of Investigative Dermatology” This study suggests that PKCß plays a critical role in modulating the dermal inflammatory microenvironment in response to dietary lipids in mice.
July 2016 in “Cancer Research” This study developed a topical botanical lotion for managing chemotherapy-induced hair loss in cancer patients, reporting that it improved hair recovery times by 5-16 weeks, reduced inflammation, and enhanced scalp collagen levels with no observed side effects.
May 2015 in “Cancer Research” This study found that a new treatment candidate may effectively prevent and promote recovery from chemotherapy-induced alopecia by normalizing apoptosis and reducing inflammation in cancer patients.
April 2012 in “Cancer Research” In this study, mouse models with EGFR deficiency showed that disrupted hair follicle cycling leads to increased mast cell numbers and inflammation, suggesting EGFR's role in managing hair cycle transitions and preventing folliculitis.
This abstract discusses the classification of scarring alopecia, distinguishing it from secondary scarring alopecia and detailing its subtypes based on inflammation patterns and cells present during the disease's active phase, but reports no new clinical results.
May 2012 in “Hair transplant forum international” This article discusses the prevalence of female pattern hair loss and reports no new results; the authors highlight its increased prevalence with aging.
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April 1993 in “Cell” This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.