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This review highlights that 5 Alpha Reductase Inhibitors, used for treating conditions like benign prostatic hypertrophy, can cause side effects that sometimes persist after stopping the medication, urging physicians to consider these drugs as potential sources of new symptoms in patients.

This review discusses current medical therapies available for treating hair loss and emphasizes the importance of understanding these options, but it presents no new results.

This case study observed that in four middle-aged men with ejaculation disorders, therapy with human chorionic gonadotropin (hCG) alone or combined with recombinant follicle-stimulating hormone (rFSH) improved sexual desire, semen volume, and various other symptoms, although some experienced elevated estradiol levels and hair loss.

This case report highlights the adverse effects of unmonitored bioidentical hormone replacement therapy, emphasizing the need for patient education about its safety and efficacy compared to FDA-regulated hormones.

This review discusses treatments for female sexual dysfunction in postmenopausal women, noting that the effectiveness of current pharmaceutical options is inconclusive and emphasizing the importance of individualized care.

Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.

This article reviews the effect of aging on male hormone levels and fertility, highlighting the need for more research on the benefits and risks of androgen supplementation in older men.

This review discusses the limitations of serum androgen measurements in diagnosing and treating women with potential androgen-related disorders and the potential role of androgen replacement therapy for those with sexual interest/arousal disorders, reporting no new results.

This review reports that 5-alpha reductase inhibitors, used to treat androgenic alopecia, may adversely affect sperm count, sexual function, and hormones in a subset of patients.

Bicalutamide may improve hair growth in postmenopausal women with mild side effects.

In this study, bilateral oophorectomy was reported as an effective treatment for normalizing androgen levels and resolving hypersexuality and related symptoms in a post-menopausal woman with ovarian hyperthecosis, suggesting its importance in addressing excess androgen production in such cases.

This review discusses hormonal changes in aging men and suggests the need for more research on androgen supplementation and partial androgen deficiency, without presenting new clinical findings.

This article discusses advancements expected in treatments for hair loss and unwanted hair, including hormonal modulation and improved laser hair removal, but reports no new clinical findings.

This article evaluates sexual function using the International Index of Erectile Function in people taking finasteride for androgenetic alopecia but does not present new findings.

This study found that dutasteride effectively improves symptoms of benign prostatic hyperplasia, showing benefits in urinary flow and quality of life, with only modestly elevated sexual side effects compared to placebo.

This review discusses the role of acyl-CoA binding protein (ACBP) in the epidermal barrier, noting that its disruption in mice is linked to skin and fur abnormalities; it reports no new clinical results.

This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.

This article reviews the clinical signs, diagnostic approaches, and treatment options for hyperandrogenism in women, focusing on hirsutism and specifies that cyproterone acetate is effective for severe cases, but reports no new clinical results.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.

This review discusses the multifactorial causes of female sexual dysfunction and reports no clinical results; it emphasizes the need for thorough evaluation before considering androgen therapy.

This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.

This review discusses the efficacy of the lipidosterolic extract of Serenoa repens for treating lower urinary tract symptoms and reports no new clinical results; the authors propose further examination of the existing literature and guidelines.

The researchers reported creating a Human Hair Atlas that maps over 1200 molecular species in hair, revealing up to 50% variation in metabolite and lipid levels along the hair's length, and identified 122 exposome-related compounds from personal care products.

This review discusses the use of antiandrogen therapy in dermatology, covering treatments for conditions like acne, hirsutism, and androgenic alopecia but reports no new clinical findings.

In this study, high-dose dutasteride significantly reduced several core symptoms of PMDD compared to placebo, supporting the role of neurosteroids in this condition.

This study found that bovine lactoferrin promotes hair growth in mice by enhancing dermal papilla cell proliferation through the Erk/Akt and Wnt signaling pathways.

The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.

This study found that finasteride significantly reduced dihydrotestosterone levels but did not provide clear evidence of impaired libido or erectile function compared to placebo in men.

This study evaluated the effects of exosome therapy from hypoxia-treated mesenchymal stem cells on a fluconazole-induced alopecia model in rats and found that it significantly reduced TNF-α and increased VEGF levels, suggesting potential as a novel regenerative treatment for alopecia.