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Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Finasteride doesn't affect hormone levels in normal men.

Finasteride doesn't affect bone density in male rats.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

The document describes a treatment for excessive hair growth in a teenage girl using medication and birth control, but does not report the results.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Finasteride helps induce ovulation in nonresponder PCOS women.

Women with PCOS who have high male hormone levels often also have insulin resistance.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Homemade hair treatments can significantly lower drug levels in hair, possibly causing false-negative drug tests.

The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Using your own blood (PRP) can effectively increase hair count and strength in men with hair loss.

Finasteride is effective in stopping hair loss and promoting regrowth in most men with mild side effects.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Lowering testosterone speeds up wound healing in male mice.

New genes and pathways are important for testosterone production and male sexual development.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.