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    Glossary In Vitro Models

    experimental systems studying biological processes outside living organisms

    In Vitro Models refer to experimental systems used to study biological processes outside of a living organism, typically in a controlled laboratory environment. These models often involve the use of cell cultures or tissue samples to investigate cellular behaviors, drug responses, or disease mechanisms, providing valuable insights without the ethical and practical complexities of in vivo (within a living organism) studies.

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    1. Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion Lab on a Chip · 2013 · 208 citations
    2. In vitro skin models to study epithelial regeneration from the hair follicle PLoS ONE · 2017 · 19 citations
    3. In Vitro Skin Models for Pigmentary Disorders: From Reconstructed Tissues to Skin-on-a-Chip Platforms Regenerative Biomaterials · 2026
    4. Modeling aging in a culture dish: towards the development of more sophisticated in vitro models of human skin aging Ageing Research Reviews · 2026
    5. Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis Biomedicines · 2020 · 26 citations
    6. Assessing the effect of cleansing products on artificially polluted human hairs and skin through in vivo and in vitro models Skin Research and Technology · 2023
    7. Bioprinted Recombinant Human-Collagen-Based In Vitro Skin Models for Assessing Effects of Nano-ZnO on Dermis Gels · 2025 · 2 citations
    8. A hair-follicle reconstructed in vitro immunocompetent skin model for prediction of the sensitizing potential of chemicals Archives of Toxicology · 2025
    9. 132 Design of an in vitro skin 3D model mimicking a disruption of the barrier function Journal of Investigative Dermatology · 2017
    10. Epidermal structure created by canine hair follicle keratinocytes enriched with bulge cells in a three‐dimensional skin equivalent model <i>in vitro</i>: implications for regenerative therapy of canine epidermis Veterinary dermatology · 2013 · 11 citations
    11. Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 α increase in epidermal in vitro model Food and chemical toxicology · 2017 · 12 citations
    12. Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument 2011
    13. Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments Journal of Investigative Dermatology · 2024 · 32 citations
    14. Advances in Bioprinting to Model Immune‐Mediated Skin Diseases Advanced Healthcare Materials · 2025
    15. <i>In vitro</i> interactions between sensory nerves, epidermis, hair follicles and capillaries in a tissue‐engineered reconstructed skin Experimental Dermatology · 2004
    16. Microscopy‐guided laser ablation for the creation of complex skin models with folliculoid appendages Bioengineering & translational medicine · 2020 · 5 citations
    17. In vitro models to study hair follicle generation Elsevier eBooks · 2017 · 5 citations
    18. Skin penetration of active folate salts and their effects on wound healing in vitro: new approaches for dermal folate application 2023 · 1 citations
    19. Influence of donor sources and culture media on the histo-morphological quality of human artificial skin models Online Publication Service of Würzburg University (Würzburg University) · 2018
    20. Comparison of two in vitro models for the analysis of follicular penetration and its prevention by barrier emulsions European journal of pharmaceutics and biopharmaceutics · 2009 · 33 citations
    21. 501 Next-generation in vitro testing: microfluidic models for aging, wound healing, and oral tissue analysis in safety, efficacy, and permeation studies Journal of Investigative Dermatology · 2024
    22. Development of a novel in vitro strategy to understand the impact of shaving on skin health: combining tape strip exfoliation and human skin equivalent technology Frontiers in Medicine · 2023
    23. Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro Journal of Tissue Engineering and Regenerative Medicine · 2020 · 29 citations
    24. Photo-responsive fibers as artificial hairs in an in-vitro model for transdermal drug delivery Research Portal Denmark · 2024
    25. General practitioner’s pitfalls of intralesional corticosteroid in alopecia areata: In vitro models Journal of the American Academy of Dermatology · 2016
    26. Senotherapeutic Potential of Araliadiol in Senescent Human Dermal Fibroblasts: An In Vitro Study Using Three Senescence Models Pharmaceutics · 2025
    27. KF19418, a new compound for hair growth promotion in vitro and in vivo mouse models Journal of Dermatological Science · 2001 · 15 citations
    28. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes Journal of Photochemistry and Photobiology B-biology · 2018 · 9 citations
    29. Protective effects of Ecklonia cava extract on the toxicity and oxidative stress induced by hair dye in in-vitro and in-vivo models Journal of oceanology and limnology (Online) · 2019 · 5 citations
    30. Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model Frontiers in Medicine · 2025 · 8 citations