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In this study, researchers found that a cold atmospheric plasma-activated hydrogel containing interleukin-2 significantly enhanced hair regeneration in a depilated mouse model, promoting larger hair follicles and faster hair growth phase transition, suggesting it as a potential treatment for hair loss.

In this study, a silk-inspired hydrogel system was developed that combines photodynamic therapy and wound healing, which may significantly reduce melanoma recurrence and enhance healing of infected wounds.

This study developed a hydrogel dressing incorporating angelica polysaccharides, demonstrating enhanced wound healing properties in a mouse model by promoting rapid hemostasis, tissue healing, and new blood vessel formation compared to Tegaderm™ film.

This study found that a bioprinted hydrogel scaffold with zinc and silicon ions significantly activated hair follicle stem cells and enhanced blood vessel formation, promoting hair growth in mouse wound models.

This study reported that polysaccharides from Astragalus roots could promote hair regeneration and optimize drug delivery when combined in innovative microneedles, effectively improving hair growth in mice with androgenetic alopecia.

RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.

This review assesses the benefits and limitations of various supramolecular hydrogels, including polymeric and peptide-based types, for wound healing, but reports no new clinical results.

This study developed the TLMG hydrogel, a seamless in situ biointerface platform, demonstrating robust adhesion, high conductivity, and therapeutic effects for intelligent wound management in complex animal models and human tests, indicating its promise for integrated bioelectronic medicine.

This study evaluated amphiphilic self-assembling peptides as drug delivery systems and found they effectively ensured prolonged release and therapeutic efficacy for timolol in glaucoma and for chemotherapy agents in cancer treatment, with significant tumor size reduction observed in animal models.

This study reports that a new artificial skin system using multi-layered hydrogels can promote scarless wound healing and regenerate appendages like hair follicles without cell transplantation.

New materials and methods could improve skin healing and reduce scarring.

This study found that a novel in-situ crosslinked self-healing hydrogel made from oxidized Bletilla striata polysaccharide and cationic gelatin enhanced wound healing and showed strong hemostatic performance in animal models, suggesting its potential as an effective wound dressing for skin trauma.

In this study, researchers used a chemical cocktail and hydrogel microspheres to successfully guide fibroblasts into dermal papilla cells, promoting wound healing and in situ hair follicle regeneration while reducing scar formation, in both in vitro and in vivo experiments.

This paper reviews recent advances in the design and use of injectable biomaterials for spinal degeneration treatment, highlighting the types of biomaterials like hydrogels and bone cements, and discussing key challenges and opportunities for clinical translation.

This study developed keratin-based hydrogels with improved water solubility and tunable properties, demonstrating excellent cytocompatibility, suggesting potential for biomedical applications.

In this study, researchers developed a versatile sprayable hydrogel that promotes wound healing in mice by facilitating rapid gelation, reducing inflammation, and accelerating tissue regeneration, with potential applications in chronic wound treatment and beyond.

This review explores the different types of hydrogels used to repair diabetic ulcers, the mechanisms involved, and the limitations in developing these technologies for clinical use, but it reports no new clinical results.

In this study, a hydrogel loaded with SHP099 was shown to improve wound healing by targeting different cell types during various stages of the healing process.

This study reported that a new bioinspired injectable hydrogel, CQCS@gel, showed promise as a multifunctional wound dressing by achieving rapid hemostasis and promoting the healing of infected skin wounds in both in vitro and in vivo tests.

This review examines the design strategies for creating conductive hydrogels with adjustable properties for various biomedical applications, highlighting their potential for supporting cell growth, wound healing, drug delivery, tissue regeneration, and biosensing.

This review reports that 3D skin bioprinting has made significant progress towards clinical application, particularly in wound healing and disease modeling, but further work on vascularization and bioink standardization remains crucial.

This review article highlighted the diverse applications of functionalized materials from bacterial cellulose, detailing advances in both in situ and ex situ methods for enhancing these materials' properties, particularly for medical applications, and proposed directions for future research.

This study found that thermoresponsive hydrogels can maintain mechanical memory in fibroblasts, enhancing wound healing compared to traditional trypsinized methods.

The hydrogel helps heal wounds without scars by releasing two drugs gradually.

This review discusses photothermal agent hybrids in hydrogels for antibacterial action, angiogenesis, and osteogenesis in tissue engineering, but reports no new experimental findings.

This study developed HA-gel-dex hydrogels with enhanced ECM-like properties and functionality, showing promise for 3D bioprinting, tissue repair, and as wound dressings due to improved cell interaction, cytocompatibility, antimicrobial synergy, and wound healing in mice compared to traditional ECM bio-inks.

This study found that the natural polymer-based hydrogel Gel/SA@PL released growth factors in a controlled way, which enhanced tissue regeneration and minimized scarring in the healing of diabetic wounds.

In a study on diabetic mice, researchers developed a protein-based hydrogel that leverages zinc ions and the natural compound phellopterin to promote cutaneous nerve regeneration, angiogenesis, and tissue remodeling in diabetic wounds, highlighting its potential for advanced wound therapy.

This review discusses recent advances in scarless wound healing, focusing on strategies to create pro-regenerative scaffolds for repairing damaged skin, and reports no new clinical results.

This study found that an injectable ceria-based nanocomposite hydrogel improved wound healing and epithelium regeneration, including hair follicle and adipocyte tissue formation, in full-thickness skin wound models.