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Soymetide-4 from soy can prevent hair loss caused by a cancer drug in rats.

This study reported that phytochemicals SA-4 and SA-6 from Tridax procumbens exhibited a dose-related immunostimulatory effect on mice, suggesting their potential as immunostimulators.

This chapter reviews treatments for alopecia areata and androgenetic alopecia but presents no new clinical findings, emphasizing the need for more effective and safe hair growth promoters.

In this study, a case of Alopecia totalis was treated using cupping therapy along with ayurvedic treatments, suggesting that the combination may be effective due to the herbs' synergistic effects and cupping's immunostimulant activity.

This study reviews previous research on the development of pharmaceutical formulations using Carthamus tinctorius L., a traditional medicinal plant with antioxidant and immunostimulant properties, identifying the creation of various forms such as syrups, emulsions, granules, and nanoparticles.

In this case report, a 2-month-old Chippiparai pup in Puducherry, India, successfully received treatment for concurrent scabies and dermatophytosis using ivermectin, a topical acaricide solution, a dewormer, and an herbal immunostimulant, with no signs of toxicity.

This case study highlights a patient with alopecia areata who experienced telogen effluvium after regrowth following diphencyprone-induced contact dermatitis.

This study reports that bioactive peptides derived from food proteins may lower serum cholesterol and exhibit antihypertensive and immunostimulating effects, suggesting potential in preventing lifestyle-related diseases.

This review highlights recent advancements in microneedle technology, noting its ability to enhance transdermal drug delivery, biosensing, cancer treatment, and skin disease repair, while emphasizing its potential for improving patient compliance and reducing side effects.

This study found that PDRN derived from Lactobacillus rhamnosus showed superior antioxidant and wound-healing properties compared to salmon-derived PDRN, while also offering potential benefits in immune modulation and bioavailability.

In this study, post-treatment with DCO was found to speed up epidermal wound healing after micro-needling of 3D skin models while maintaining the treatment's immunostimulatory benefits, potentially optimizing aftercare and reducing patient recovery time.

In this review, the authors highlighted the potential of natural polysaccharides from plants, animals, and microbes to modulate immune responses, reduce inflammation, and strengthen the intestinal barrier, suggesting their promising role as immunomodulatory agents in pharmaceutical applications.

Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.

This article in Experimental Dermatology does not include an abstract or any new research findings.

In this review, researchers examined the physiological benefits of Cheonggukjang, a salt-free fermented soybean paste, highlighting its various health-promoting components that may contribute to improved heart health, diabetes management, and cancer prevention, among other benefits.

This review discusses the chemical constituents and diverse pharmacological activities of Glycyrrhiza glabra (liquorice) but reports no new clinical results, emphasizing its potential for developing new therapeutic formulations.

In this clinical study, melatonin treatment reduced oxidative stress markers and enhanced hair growth in patients with alopecia areata, potentially through its effects on the immune system and antioxidant activity.

In this case study, a 46-year-old woman with tattoos and a history of hypothyroidism developed autoimmune-like symptoms, highlighting the importance of distinguishing ASIA syndrome from other immune disorders and assessing potential adjuvant exposure.

This study outlines new strategies for overcoming "cold" tumors, which are typically unresponsive to cancer immunotherapy, with approaches like dendritic cell-based treatments and local immune microenvironment modification, bolstered by both preclinical and clinical trial data.

This study tested a hydrogel microneedle patch delivering T reg attractants in mice with alopecia, finding it boosted regulatory T cell numbers at the site, leading to hair regrowth without causing peripheral immunosuppression, suggesting a potential new approach for autoimmune skin disease treatment.

This review discusses the use, mechanism, and side effects of topical immunomodulators in treating immune-mediated skin disorders and reports no new clinical results, urging further research on experimental agents.

This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.

This report describes a case of polymyositis that was resistant to steroids and immunosuppressants but showed improvement with immunoadsorption therapy.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.

In this study, only a subset of proposed biomarkers universally responded to priming in mesenchymal stromal cells, suggesting limited utility for standardized potency assays across different MSC types and conditions.

This study reported that intensive immunosuppression in multiple sclerosis patients significantly reduced relapse rates versus pre-treatment expectations, though some required ongoing treatment after tapering.

This review highlights the potential of microneedles for immunotherapy, emphasizing their ability to enhance immune responses and reduce side effects through precise and stimuli-responsive delivery, especially in tumor treatment, while also noting the limitations and areas for improvement in current systems.