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Neurohormones help control skin health and could treat skin disorders.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.

New treatments for skin and hair repair show promise, but further improvements are needed.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Alopecia areata causes hair loss, has no cure, and various treatments exist.