research Clinical Usefulness of Plasma Androstanediol Glucuronide Measurements in Women with Idiopathic Hirsutism
Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.
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research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Update on Idiopathic Hirsutism: Diagnosis and Treatment
The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
research Retinol-Binding Protein 4, Leptin, and Insulin Resistance in Idiopathic Hirsutism and Hirsute Women with Polycystic Ovary Syndrome
Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.
research Finasteride And Flutamide In The Treatment Of Hirsutism
Finasteride and flutamide can effectively treat hirsutism, with abdominal hairs showing the most sensitivity to the treatment.
research CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
research A Study on Clinical Profile of Patients with Hirsutism
Most women with excess hair growth had Polycystic Ovary Syndrome, and severity wasn't linked to hormone levels.
research Incidence of Serious Infectious Events with Methotrexate Treatment: Meta-Analysis of Randomized Controlled Trials
Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.
research CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
research ELife Assessment: CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells
CaBP1 and 2 are important for maintaining the activity of calcium channels necessary for hearing in inner ear cells.
research Zinc Deficiency Triggers Hearing Loss by Reducing Ribbon Synapses of Inner Hair Cells in CBA/N Mice
Lack of zinc can cause hearing loss by damaging important parts of inner ear cells in mice.
research A Preliminary Study of Melanogenic Markers in the Differentiation of the Human Hair Follicle Melanin Unit
The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
research Delayed Puberty: Diagnosis and Management of Congenital Idiopathic Hypogonadotropic Hypogonadism
A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.
research Urinary Symptoms in Patients with Androgenetic Alopecia
Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.
research Clinical and Hormonal Evaluation of Androgen Excess
Most cases of high male hormone levels in women are due to polycystic ovary syndrome.
research Correction to 'Divergent Progression Pathways in Male Androgenetic Alopecia and Female Pattern Hair Loss: Trichoscopic Perspectives'
The document corrects errors in a table about hair loss in women.
research Hypothyroidism with Multiple Associations: Case Report
The patient with autoimmune hypothyroidism improved after treatment for thyroid and associated conditions.
research Adult Onset Isolated Hypogonadotropic Hypogonadism: A Cause of Secondary Amenorrhea
A 23-year-old woman's missed periods were caused by a rare genetic disorder treated with hormone patches.
research Editor's Choice: November 2017 British Journal of Dermatology Highlights
Organ transplant recipients have a higher risk of skin cancer over time, atopic dermatitis skin shows unusual bacterial and fungal patterns, a new tool for measuring hidradenitis suppurativa severity was created, and gene expression changes in male baldness suggest new treatments.
research Mammalian Target of Rapamycin Complex 1 (mTORC1) May Modulate the Timing of Anagen Entry in Mouse Hair Follicles
A protein complex called mTORC1 likely affects when hair growth starts in mice.
research Role of the Wnt Signaling Pathway in Keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
research The Expressions of Androgen Receptors and Estrogen Receptors in Bald and Non-Bald Areas of Androgenic Alopecia
Hair loss in androgenic alopecia may be linked to increased local androgen activities, but not to estrogen levels.
research ABO Blood Grouping of Non-Medullated Scalp Hair Using Immunohistochemical Staining
The modified staining method can determine the ABO blood group of hair samples accurately.
research Is Obesity Surpassing Conventional Risk Factors in the Development of Coronary Artery Disease, Irrespective of Age?
Obesity is an independent risk factor for early coronary artery disease (CAD) and its severity is not affected by age.
research Association of Small, Dense LDL Cholesterol With Acute Myocardial Infarction in Young Population
Higher levels of small, dense LDL cholesterol are linked to a greater risk of heart attack in young adults.
research Reconstruction of Scalp and Forehead Defects: Options and Strategies
Local flaps are effective for covering small to large scalp and forehead defects with good cosmetic results.
research Premature Greying and Androgenic Alopecia as Independent Predictors of Underlying Coronary Artery Disease in Young Asian Males
Early greying and male pattern baldness can predict heart disease in young Asian men.
research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research Transgenic Mice Display Hair Loss and Regrowth Overexpressing Mutant Hr Gene
Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.
research The Extract of Thuja Occidentalis Semen Inhibited 5α-Reductase and Androgenetic Alopecia in B6CBAF1/J Hybrid Mice
Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.