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    Glossary IGF-1 Receptor

    protein on cell surfaces that binds to growth hormone IGF-1

    The IGF-1 Receptor (Insulin-like Growth Factor 1 Receptor, IGF1R) is a protein found on the surface of human cells that binds to the hormone IGF-1. This interaction plays a crucial role in cell growth, development, and survival. In the context of hair biology, IGF-1 and its receptor are important for hair follicle development and the regulation of hair growth cycles.

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    1. Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways Animals · 2023 · 1 citations
    2. Glucagon-Like Peptide-1 Receptor Agonists and Hair Loss: Current Evidence and Potential Mechanisms JAAD reviews. · 2026
    3. A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control Experimental Dermatology · 2004 · 2 citations
    4. The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia International Journal of Biological Sciences · 2023 · 2 citations
    5. MLPH-mediated activation of dermal papilla IGF-1 signaling drives human hair shaft elongation and anagen induction Biomedicine & Pharmacotherapy · 2026
    6. Role of ASLNC168501 in regulating hair follicle stem cell activity via the AR/miR-128-3p/IGF-1 pathway Stem Cell Research & Therapy · 2026
    7. Ar/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia Social Science Research Network · 2022
    8. 0980 Tanshinone capsule enhances hair follicle regeneration in a mouse model of androgenetic alopecia via IGF1 and Wnt/β-catenin pathway Journal of Investigative Dermatology · 2026
    9. EGFR marks a subpopulation of dermal mesenchymal cells highly expressing IGF1 which enhances hair follicle regeneration. PubMed · 2023 · 1 citations
    10. Investigation of Insulin-Like Growth Factor 1 Receptor Expression in Cases of Sacrococcygeal Pilonidal Sinus Medical records-international medical journal · 2023
    11. Role of insulin-like growth factor-1 receptor in female androgenetic alopecia Menoufia Medical Journal · 2020
    12. Insulin-like growth factor 1 and hair growth Dermatology Online Journal · 1999 · 98 citations
    13. Self-assembling peptide inspired by insulin and type 1 insulin-like growth factor for the treatment of androgenetic alopecia Bioactive Materials · 2025
    14. Role of insulin, insulin‐like growth factor‐1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris Experimental dermatology · 2009 · 200 citations
    15. Olfactory receptor OR2AT4 regulates human hair growth Nature Communications · 2018 · 82 citations
    16. Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells The Journal of Urology · 2008 · 25 citations
    17. 503 A new chemosensory control of human hair growth: Olfactory receptor OR10J1 stimulation promotes scalp hair follicle growth and progenitor cell generation ex vivo Journal of Investigative Dermatology · 2024
    18. Erythropoietin induces insulin-like growth factor-1 from three-dimensional culture of human dermal papilla cells Journal of Dermatological Science · 2012
    19. 1049 Novel strategy to promote hair follicle growth and stem cell activation in human male scalp skin: Targeting prolactin receptor with ABS-201 Journal of Investigative Dermatology · 2026
    20. The Insulin-like Growth Factor 1 Receptor Is Expressed by Epithelial Cells with Proliferative Potential in Human Epidermis and Skin Appendages: Correlation of Increased Expression with Epidermal Hyperplasia Journal of Investigative Dermatology · 1996 · 128 citations
    21. The roles of hepatocyte growth factor family members in androgen-regulation of human hair growth. A comparison of the expression of hepatocyte growth factor family members, HGF and MSP, and their receptors, c-Met and RON, in isolated hair follicles from normal and androgenetic alopecia (balding) scalp. 2010
    22. Heat stress decreased hair follicle population in rex rabbits Journal of animal physiology and animal nutrition · 2018 · 10 citations
    23. Naturally Occurring Hair Growth Peptide: Water-Soluble Chicken Egg Yolk Peptides Stimulate Hair Growth Through Induction of Vascular Endothelial Growth Factor Production Journal of Medicinal Food · 2018 · 6 citations
    24. 1303 Insights gained from a chickens rapid hair development during hatching lead to discovery of hair growth peptide derived from egg yolk Journal of Investigative Dermatology · 2018
    25. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995 · 173 citations
    26. Molecular Genetic and Endocrine Mechanisms of Hair Growth Hormone Research in Paediatrics · 2003 · 51 citations
    27. CRISPR/Cas9-mediated<i>VDR</i>knockout plays an essential role in the growth of dermal papilla cells through enhanced relative genes PeerJ · 2019 · 2 citations
    28. Anti-Hair Loss Effect of Adenosine Is Exerted by cAMP Mediated Wnt/β-Catenin Pathway Stimulation via Modulation of Gsk3β Activity in Cultured Human Dermal Papilla Cells Molecules · 2022
    29. Recent Advances in Hair Biology and in Treatments of Androgenetic Alopecia. Journal of S C C J · 1999
    30. Role of insulin resistance and diet in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 39 citations