20 citations
,
December 1997 in “Clinical Endocrinology” This article discusses the potential beneficial effect of spironolactone on androgenic alopecia but provides no new clinical findings.
6 citations
,
February 1996 in “Clinical Pharmacology & Therapeutics” Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.
90 citations
,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
23 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical minoxidil and diazoxide induced significant hair regrowth in bald macaques, while a steroid 5 alpha-reductase inhibitor prevented baldness in preadolescent macaques.
14 citations
,
April 2009 in “Acta Medica Scandinavica” In this study, oral minoxidil combined with other medications improved blood pressure control in patients with severe hypertension but often had to be discontinued due to side effects.
November 2024 in “Rheumatology Advances in Practice” Early recognition and treatment of SLE can improve outcomes in patients with complex symptoms.
223 citations
,
January 2000 in “BioFactors” This study reports that bioactive peptides derived from food proteins may lower serum cholesterol and exhibit antihypertensive and immunostimulating effects, suggesting potential in preventing lifestyle-related diseases.
100 citations
,
March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.
29 citations
,
May 2018 in “Clinical Endocrinology” This review discusses the differential diagnosis of low-renin hypertension and highlights recent genetic discoveries related to familial forms, but it presents no new clinical results.
7 citations
,
January 2021 in “Cureus” This case report describes a 27-year-old woman who experienced facial swelling due to allergic contact dermatitis from using minoxidil 5% foam.
6 citations
,
July 1990 in “The Journal of Pediatrics” A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.
6 citations
,
January 1984 in “PubMed” This study found that spironolactone reduced androgenic hormones in hirsute women but had only marginal effects on hair growth, making it no more advisable than other therapies.
4 citations
,
December 1997 in “Clinical Endocrinology” This article presents a case of giant cell arteritis occurring in a patient with de Quervain's thyroiditis but reports no new clinical findings.
2 citations
,
October 2012 in “Cutaneous and Ocular Toxicology” This study suggests that glaucoma patients may face increased risk of optic nerve injury if prescribed medications that can lower blood pressure.
1 citations
,
February 2005 in “The Lancet” Hair loss may be linked to cardiovascular health problems.
September 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil does not significantly affect blood pressure in patients with hair loss and hypertension.
May 2024 in “Journal of clinical case studies reviews & reports” This case report detailed a unique instance of hypopituitarism in a 65-year-old male presenting with symptoms including nausea, vomiting, and fatigue, attributed to secondary adrenal insufficiency, which improved following appropriate cortisol treatment.
April 2021 in “The journal of heart and lung transplantation/The Journal of heart and lung transplantation” This case report describes a woman with Sheehan's syndrome, leading to severe combined systolic and diastolic heart failure, where treatment improved cardiac function.
October 2015 in “Elsevier eBooks” Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.
January 2014 in “American Journal of Medicine and Medical Sciences” This article discusses the mechanisms of androgenetic alopecia and explores possible explanations for minoxidil's effect on hair growth but reports no new results.
180 citations
,
July 1973 in “The New England Journal of Medicine” In this study, minoxidil effectively reduced blood pressure to near normal levels in patients with malignant or accelerated hypertension resistant to conventional treatments, offering a potential alternative to nephrectomy.
55 citations
,
October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
51 citations
,
October 1980 in “The New England Journal of Medicine” Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
38 citations
,
March 2020 in “Current Hypertension Reports” This review discusses how various reproductive factors are linked to increased risks of hypertension and cardiovascular disease, noting associations with impaired fetal growth, male hypogonadism, and effects of contraceptive use, but reports no new results.
26 citations
,
December 2023 in “Prostate International” This review provides an overview of the risks and side effects associated with common medications used to treat benign prostatic hyperplasia, highlighting the importance for clinicians and patients to discuss these aspects for informed decision-making.
16 citations
,
March 1981 in “PubMed” This study found that minoxidil significantly reduced blood pressure in patients with intractable hypertension and was generally well-tolerated, although fluid retention and hirsutism posed some challenges.
14 citations
,
November 2006 in “Current Medicinal Chemistry” This review discusses recent developments in α1-adrenoceptor antagonists and 5α-reductase inhibitors for treating benign prostatic hyperplasia, reporting no new clinical results while identifying potential areas for future drug development.
5 citations
,
January 2018 in “Javma-journal of The American Veterinary Medical Association” This case report documents the first successful management of accidental minoxidil toxicosis in a dog, resulting in full recovery after treatment with supportive care, including medications for blood pressure and potential toxicity mitigation.
5 citations
,
January 2017 in “Acta Endocrinologica” This case report discusses a postmenopausal woman whose hyperandrogenism and metabolic symptoms improved significantly after the surgical removal of an ovarian Leydig cell tumor, confirmed post-operatively.
4 citations
,
May 2021 in “Research Journal of Science and Technology” This review discusses the therapeutic applications of Hibiscus rosa sinensis and reports no new clinical results; the authors highlight its potential in herbal medicine.