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Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Women with PCOS are much more likely to have sleep problems and should be checked for them.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.

Finasteride doesn't affect bone density in male rats.

Finasteride doesn't affect bone density in male rats.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Testosterone is crucial for development, growth, and various body functions in mammals.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.