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    Research 511–540 of 946

    1. Phospholipase C 1 is required for skin stem cell lineage commitment The EMBO Journal · 2003 · 101 citations
    2. Cell fate decisions: emerging roles for metabolic signals and cell morphology EMBO Reports · 2017 · 100 citations
    3. Pulmonary manifestations of Birt-Hogg-Dubé syndrome Familial cancer · 2013 · 99 citations
    4. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity The Journal of Cell Biology · 2015 · 98 citations
    5. Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation PLoS ONE · 2007 · 98 citations
    6. Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases Frontiers in Cell and Developmental Biology · 2019 · 97 citations
    7. Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration The FASEB Journal · 2016 · 94 citations
    8. Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle 2003 · 94 citations
    9. Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development Proceedings of the National Academy of Sciences of the United States of America · 2003 · 93 citations
    10. Microneedles as transdermal drug delivery system for enhancing skin disease treatment Acta Pharmaceutica Sinica B · 2024 · 91 citations
    11. NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor The EMBO Journal · 2019 · 91 citations
    12. Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size Molecular Cell · 2018 · 90 citations
    13. Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction Journal of Cell Science · 2009 · 87 citations
    14. Protein Kinase C as a Therapeutic Target Clinical Cancer Research · 2006 · 87 citations
    15. Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease Journal of Cell Science · 2008 · 85 citations
    16. The role of PPAR<i>γ</i>-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology Experimental Dermatology · 2015 · 84 citations
    17. Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells International Journal of Molecular Sciences · 2013 · 83 citations
    18. RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 82 citations
    19. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice EMBO molecular medicine · 2014 · 81 citations
    20. The Two Functional Keratin 6 Genes of Mouse Are Differentially Regulated and Evolved Independently from Their Human Orthologs Genomics · 1998 · 79 citations
    21. Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis Journal of Investigative Dermatology · 2007 · 78 citations
    22. Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds Cell Communication and Signaling · 2024 · 74 citations
    23. The importance of the neuro‐immuno‐cutaneous system on human skin equivalent design Cell Proliferation · 2019 · 73 citations
    24. The role of the microbiome in scalp hair follicle biology and disease Experimental Dermatology · 2019 · 73 citations
    25. Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion PloS one · 2012 · 72 citations
    26. Estrogen Receptor α, but not Estrogen Receptor β, is Involved in the Regulation of the Hair Follicle Cycling as well as the Thickness of Epidermis in Male Mice Journal of Investigative Dermatology · 2002 · 72 citations
    27. Insulin Resistance and Skin Diseases The Scientific World Journal · 2015 · 71 citations
    28. Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice Journal of Clinical Investigation · 2004 · 65 citations
    29. Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice Journal of Clinical Investigation · 2004 · 64 citations
    30. Life before and beyond blistering: The role of collagen XVII in epidermal physiology Experimental Dermatology · 2018 · 63 citations