research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
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research Hirsutism: Diagnosis and Management
The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
research Effect of Finasteride and/or Terazosin on Serum PSA: Results of VA Cooperative Study #359
Finasteride reduces PSA levels, terazosin doesn't affect them, and tracking prostate cancer in patients taking finasteride could be difficult.
research Finasteride and Sexual Side Effects
Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
research Non-Polycystic Ovary Syndrome–Related Endocrine Disorders Associated with Hirsutism
Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.
research Reduced Levels of 5-Alpha Reductase 2 in Adult Prostate Tissue and Implications for BPH Therapy
Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.
research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
research Antiandrogens: Clinical Applications
Antiandrogens help treat hormone-related conditions in both men and women.
research 5-Alpha Reductase Deficiency
5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.
research Side Effects of 5-Alpha Reductase Inhibitors: A Comprehensive Review
5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
research Differential Diagnosis of Hyperandrogenism in Women with Polycystic Ovary Syndrome
The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.
research Maximum Efficacy of Finasteride Is Obtained Within 6 Months and Maintained Over 6 Years
Finasteride works best in 6 months and lasts 6 years.
research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia
Large prostate links to more hair loss, but age of onset doesn't affect it.
research Premature Adrenarche: Early Maturation of Adrenal Glands in Children
Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Cardiovascular Risk Factors and Events in Women with Androgen Excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research The Effect of 5-Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
research Clinical Relevance of Testosterone and Dihydrotestosterone Metabolism in Women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Post-Finasteride Syndrome: A Surmountable Challenge for Clinicians
Finasteride can cause serious side effects in some men, needing more research for treatment.
research Improvement in Androgenetic Alopecia in 53-76-Year-Old Men Using Oral Finasteride
Finasteride increases hair count in middle-aged and elderly men without causing sexual dysfunction.
research Incidence of Type 2 Diabetes Mellitus in Men Receiving Steroid 5α-Reductase Inhibitors: Population-Based Cohort Study
Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
research Finasteride-Associated Cataract And Intraoperative Floppy-Iris Syndrome
Finasteride may cause cataracts and floppy-iris syndrome.
research In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride
Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
research Does a Male Polycystic Ovarian Syndrome Equivalent Exist?
Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
research Long-Term Use of 5α-Reductase Inhibitors and the Risk of Male Breast Cancer
Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.
research 5α-Reductase Inhibitors, Antiviral and Anti-Tumor Activities of Some Steroidal Cyanopyridinone Derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research The Placebo Effect And Randomized Trials: Analysis Of Conventional Medicine
The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.
research Assessing Finasteride-Associated Sexual Dysfunction Using the FAERS Database
Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
research The Effects of Lovastatin on Conventional Medical Treatment of Lower Urinary Tract Symptoms with Finasteride
Lovastatin doesn't improve lower urinary tract symptoms treatment.