1 citations
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September 2024 in “Journal of Clinical & Translational Endocrinology” This study found that women with polycystic ovary syndrome have more pronounced metabolic alterations and higher androgen levels compared to women with eumenorrheic hyperandrogenism, suggesting EuHyperA may be a milder form of PCOS.
November 2025 in “Anxiety Stress & Coping” This study found that generalized anxiety disorder symptoms predicted higher emotional distress and hair cortisol concentration, with dominance unexpectedly increasing the impact of anxiety on hair cortisol.
11 citations
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April 2020 in “Animals” This study reported that relocation in police horses was associated with elevated hair cortisol concentrations, possibly suggesting altered welfare due to changed surroundings, and that seasonal variations affected both cortisol levels and hair growth.
October 2020 in “Journal of the American Society of Nephrology” In this case study, drospirenone use masked the diagnosis of a rare form of congenital adrenal hyperplasia, suggesting a possible delay in detecting underlying endocrinopathies.
October 2024 in “Journal of the Endocrine Society” This case report highlighted a rare instance of Cushing's syndrome caused by ectopic ACTH from cervical cancer, demonstrating diagnostic challenges, treatment complexity, and high risks of morbidity and mortality, with less than 10 cases documented overall.
188 citations
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January 2022 in “PubMed” This review discusses recent advancements in congenital adrenal hyperplasia research, including improved diagnostic techniques, alternative treatments, and insights from long-term outcome data, but it reports no new clinical results.
December 2024 in “Journal of Clinical Research in Pediatric Endocrinology” This study explains that congenital adrenal hyperplasia due to 21-hydroxylase deficiency presents as a continuous phenotype and involves symptoms ranging from virilization to accelerated growth in children, with diagnosis relying on clinical, biochemical, and genetic evaluation.
August 2017 in “ARSHI Veterinary Letters” This case report describes a 10-year-old Shih Tzu diagnosed with hyperadrenocorticism, leading to the management of skin issues which initially improved but was followed by neurological symptoms, prompting euthanasia.
October 2024 in “Journal of the Endocrine Society” This case report highlights the challenge of differentiating between non-classical adrenal hyperplasia and steroid cell tumors of the ovary in a patient presenting with hyperandrogenism.
April 2020 in “Journal of the Endocrine Society” This case report emphasizes the importance of recognizing non-classic congenital adrenal hyperplasia as a cause of hyperandrogenism and the need for genetic counseling given potential familial implications.
1 citations
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November 2013 This study identified hypogonadism in 65% of men with Cushing syndrome, suggesting glucocorticoid excess may affect the hypothalamic-pituitary level or testosterone metabolism.
296 citations
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October 2018 in “General and Comparative Endocrinology” This review discusses the use of hair cortisol concentration as a marker for chronic stress and long-term cortisol secretion in animals, highlighting its benefits and the need for standardized sampling protocols.
February 2017 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair cortisol measurement is a promising, non-invasive tool for monitoring cortisol exposure over time.
94 citations
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study describes the first case of female pseudohermaphroditism due to a novel homozygous glucocorticoid receptor gene mutation, indicating possible pre- and postnatal virilization in affected females.
31 citations
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July 2004 in “Molecular Medicine” This study found that mutant glucocorticoid receptors have defective transcriptional activity and dynamic motility issues in the nucleus, likely due to impaired interactions with nuclear molecules necessary for gene activation.
2 citations
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August 2011 in “Revista Medica De Chile” This case report describes a woman with virilization syndrome who experienced a reduction in androgen levels and reversal of alopecia after removal of a Leydig cell tumor from her ovary.
199 citations
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July 2007 in “General and Comparative Endocrinology” In this study, researchers found a significant positive association between cortisol levels in hair and feces of domestic cats and dogs, suggesting hair cortisol assays could be a viable option for monitoring chronic stress.
62 citations
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March 2011 in “European journal of endocrinology” This study found that parents identified with cryptic NCCAH through genetic testing are mostly asymptomatic but may experience temporary female infertility and require glucocorticoid stress coverage in specific circumstances.
October 2012 in “Semina. Ciências Agrárias” This case report details a 7-year-old Shih Tzu with pituitary-dependent hyperadrenocorticism, where initial trilostane treatment did not improve skin conditions, necessitating a dosage increase.
1 citations
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January 2016 in “Revista Brasileira de Higiene e Sanidade Animal” This study of a Yorkshire dog with chronic dermatological alterations highlights the diagnostic importance of combining complementary laboratory tests like histopathology and serum biochemistry with clinical examination.
16 citations
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May 2020 in “Psychoneuroendocrinology” This study observed that Parkinson’s disease patients had higher hair cortisone, but not cortisol, levels compared to controls, and cortisone was significantly associated with mood-related non-motor symptoms.
3 citations
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January 2017 in “Gynecological endocrinology” This case report describes a 63-year-old woman with hyperandrogenism due to an ectopic adrenal gland adenoma on the ovaries, successfully treated with bilateral salpingo-oophorectomy.
122 citations
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October 2013 in “PEDIATRICS” This study observed that cortisol concentrations in hair, indicating prolonged stress, are correlated between mothers and young children, suggesting potential heritable traits or maternal influence.
January 2018 in “Digital Scholarship - UNLV (University of Nevada Reno)” This study found significantly higher hair cortisol concentrations in black children compared to white children aged 1-4 years, suggesting racial differences in cumulative stress as measured by hair cortisol.
88 citations
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April 2017 in “Journal of Pediatric and Adolescent Gynecology” This review discusses the pathophysiology, diagnosis, and treatment of congenital adrenal hyperplasia, but reports no new research results.
13 citations
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August 2020 in “Der Hautarzt” This article discusses hyperandrogenism, including its symptoms, causes, and diagnostic approaches, and reports no new clinical results; it emphasizes the role of interdisciplinary care in treatment.
January 2026 in “Open Science Framework”
11 citations
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January 2013 in “Indian Journal of Endocrinology and Metabolism” This case study describes an extremely rare instance of androgen-secreting adrenocortical carcinoma in a patient with non-classical congenital adrenal hyperplasia.
Higher pre-pregnancy BMI is linked to more stress in mothers and more behavioral problems in two-year-old children.
7 citations
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October 2010 in “Medical Hypotheses” Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.