9 citations
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January 2015 in “Veterinary record case reports” This study reports the first successful treatment of a dog infected with Mycobacterium avium subspecies hominissuis using antibiotics, with no zoonotic transmission observed.
June 2022 in “Rheumatology research” This case report suggests that systemic lupus erythematosus can be a rare cause of severe hypercalcemia, potentially due to stimulating parathyroid hormone receptor autoantibodies.
52 citations
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May 1982 in “The American journal of the medical sciences” This study found that the most likely cause of hypercalcemia in a patient with symptoms of hypervitaminosis A and a history of chronic vitamin A ingestion was vitamin A toxicity.
6 citations
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March 2018 in “Proceedings - Baylor University. Medical Center” This case report describes a patient with sarcoidosis who experienced severe symptomatic hypercalcemia, scarring alopecia, and acute-on-chronic kidney failure.
October 2025 in “Journal of the Endocrine Society” In this case report, the coexistence of hypercalcemia and androgen excess in a postmenopausal woman was linked to primary hyperparathyroidism and a suspected androgen-secreting ovarian tumor, underscoring the need for a comprehensive diagnostic approach to identify overlapping endocrine disorders.
August 2022 in “JAAD case reports” This case report describes a 36-year-old woman with hidradenitis suppurativa whose condition progressed to rapidly fatal squamous cell carcinoma, highlighting the potential for aggressive tumor development linked to specific protein markers.
April 2020 in “Journal of the Endocrine Society” This case report details an atypical presentation of Hodgkin's lymphoma in an 87-year-old man, where severe hypercalcemia and mental status changes prompted further investigation and diagnosis.
October 2011 in “Journal of dermatology” A man with a rare skin condition and a new gene mutation developed high calcium levels due to his treatment.
October 2022 in “British Journal of Dermatology” In this retrospective study, the incidence of hyperkalaemia within the first year of spironolactone use was assessed among women over 65 with female-pattern hair loss, highlighting a potential safety concern.
This study found that holding abatacept infusions for four weeks or longer before elective hip or knee arthroplasty did not reduce the risk of post-operative infections or readmissions.
May 2024 in “Endocrine practice” In this case report, researchers identified Vitamin A toxicity as the cause of refractory hypercalcemia in a nonverbal patient, emphasizing the difficulty of diagnosing this rare condition due to its nonspecific symptoms.
24 citations
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June 2010 in “Clinics in Dermatology” This review discusses various potential adverse effects of common oral vitamin and mineral supplements used in dermatology and highlights lesser-known issues like hematologic and neurologic effects from zinc.
This case report describes a 14-year-old girl with coeliac disease who presented with severe hypercalcaemia due to a parathyroid adenoma, which resolved after its excision.
36 citations
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February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that vitamin D receptor activation in primary keratinocytes can occur independently of the 1,25-dihydroxyvitamin D3 ligand, likely through interaction with retinoid X receptors.
21 citations
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January 1997 in “Nephron” In this study, two dialysis patients with high plasma silicon levels exhibited symptoms like painful skin eruptions and unusual hair growth, suggesting silicon may influence calcium metabolism similarly to aluminum.
12 citations
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December 1965 in “Immunology and Cell Biology” This study found that experimentally induced calcification in rat skin led to rapid and localized mineralization in hair follicles, progressing to more extensive calcification with prior hypercalcemic treatment.
11 citations
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June 1996 in “Nutrition” Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.
7 citations
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December 1971 in “Calcified Tissue Research” Hair follicles in injured skin can quickly accumulate minerals, especially calcium and phosphorus.
3 citations
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November 2021 in “World Journal of Clinical Pediatrics” This study observed that vitamin D therapy may help manage alopecia areata, totalis, and universalis, with promising hair regrowth in some pediatric cases, though further trials are needed.
2 citations
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December 2021 in “Cureus” This review discusses the potential link between low serum vitamin D levels and androgenetic alopecia and reports that vitamin D might be useful for diagnosis and treatment, but no new clinical results are included.
2 citations
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December 1973 in “Calcified tissue research” This study proposed a hypothesis for cutaneous calcinosis, suggesting that feeding DHT and subsequent epilation lead to ATP release and calcium orthophosphate formation, initiating calcification in rats.
1 citations
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January 1980 in “Side effects of drugs annual” This chapter reviews various adverse effects associated with vitamins, including hypercalcemia from high doses of vitamin A, hair loss from retinoid treatment, and complications with vitamin B6 in Parkinson's therapy, but reports no new clinical findings.
October 2025 in “Journal of the Endocrine Society” In this case report, an 80-year-old woman experienced elevated alkaline phosphatase levels due to the use of Viviscal hair supplements. Her levels returned to normal after discontinuing the supplement, highlighting the need for clinicians to consider supplements as potential causes of abnormal lab results.
January 2024 in “JCEM case reports” In this clinical case report, a man with Birt Hogg Dube syndrome presented with parathyroid cancer, the first such case according to the authors, highlighting a potential link between Folliculin gene mutations and parathyroid cancer development.
July 2023 in “Media Dermato Venereologica Indonesiana” In this study, researchers highlighted that in sarcoidosis, macrophages in granulomas can produce vitamin D, potentially leading to calcium imbalances, where vitamin D supplementation may cause hypercalcemia, necessitating careful laboratory assessment before supplementation.
May 2021 in “Journal of the Endocrine Society” This case report describes the rare association of an ovarian Leydig cell tumor and primary hyperparathyroidism in a postmenopausal woman, highlighting the importance of considering rare causes in patients with virilizing symptoms.
This case study reports that prolonged high-dose vitamin A intake led to multiple adverse health effects in a young man, which mostly resolved after stopping the supplement, although liver changes persisted.
January 1982 in “Side effects of drugs annual” This review discusses the therapeutic effects of vitamins, highlighting risks such as liver damage from prolonged high doses of vitamin A and hypercalcemia from excessive vitamin D, while noting a case of allergic reaction to vitamin B12.
This research review found that spironolactone can significantly improve acne severity more effectively than a placebo, with 73.3% of patients reporting satisfaction despite a 26.7% rate of adverse events among the 1,548 participants studied.
November 2019 in “BMC veterinary research” This study concluded that moderate to severe alopecia in Belgian Blue crossbred calves was due to malabsorption of dietary fat caused by a mixing error of milk replacer.