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The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Myrtle has various health benefits and potential for medicine development.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Frequent hair coloring and styling can damage hair and cause breakage or loss.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.