research Ethosome as a Potential Transdermal Drug Delivery System
Ethosomes are a promising way to deliver drugs through the skin.
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research In Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device
The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
research Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream
Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
research Dissolvable Microneedles Loaded with Ginsenoside Rg3 Liposome: A Transdermal Delivery Approach for Alopecia Treatment
Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.
research What's New in Dermatological Research?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research Effects of Acute UVB on Retinoid Metabolism
UVB exposure increases skin proteins for retinoic acid synthesis and shifts their location, possibly affecting skin repair.
research Distribution of Caspase-14 in Epidermis and Hair Follicles Is Evolutionarily Conserved Among Mammals
Caspase-14 is important for skin and hair development in all mammals.
research Topical Delivery of Drugs Using Ethosomes: A Review
Ethosomes improve drug delivery through the skin and show promise for treating male pattern baldness.
research Novel Insights Into Ascorbic Acid Skin Permeation
The best way to apply vitamin C to the skin is with a nanostructured lipid carrier formulation.
research Tight Junctions Form a Barrier in Porcine Hair Follicles
Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
research Increasing the Percutaneous Absorption and Follicular Penetration of Retinal by Topical Application of Proretinal Nanoparticles
Proretinal nanoparticles improve skin absorption and reduce irritation of topical retinoids.
research Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls
Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Using hair follicles can improve skin drug delivery.
research Ex Vivo Permeation Parameters and Skin Deposition of Melatonin-Loaded Microemulsion for Treatment of Alopecia
Melatonin-loaded microemulsion could be a promising treatment for hair loss.
research Targeted Skin Delivery of Topically Applied Drugs by Optimized Formulation Design
Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.
research Epidermal Barrier
Healthy skin prevents water loss and protects against threats.
research Targeted Delivery of Zinc Pyrithione to Skin Epithelia
Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
research Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
research A Finasteride Patch for the Treatment of Androgenetic Alopecia: Study on Permeability Strategy Using Synthetic O-Acylmenthols and Ion-Pair
The finasteride patch effectively treats hair loss by enhancing skin absorption.
research Variations of Hair Follicle Size and Distribution in Different Body Sites
Hair follicle size and distribution vary significantly across different body sites.
research Podophyllotoxin-Loaded Solid Lipid Nanoparticles for Epidermal Targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Comparison of Artificial Sebum with Human and Hamster Sebum Samples
Artificial sebum L closely mimics human sebum for drug delivery research.
research Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In Vitro Human Skin Studies
Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Downregulation of Nuclear Factor-KappaB Activation in Human Keratinocytes by Melanogenesis Inhibitors
Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.
research Developing Human Fetal Skin Demonstrates a Unique Lymphocyte Signature
Fetal skin has unique immune cells different from adult skin.