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The keratin network in mouse skin changes during cornification and affects the skin's protective barrier.

Human skin has less GDNF and its receptor with age.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Skin has a larger surface area than thought, certain skin cells improve skin flap survival, better trials for skin conditions in children are needed, Stevens-Johnson syndrome rates vary by age and race, and better skin barrier function may reduce inflammation in the elderly.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.

Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Fish oil improves skin health in people with diabetes and high cholesterol.

Dermatologists should customize cosmetic treatments for dark-skinned patients to minimize risks and complications.

Horse skin has a layered epidermis, a dermis with hair follicles, sweat and sebaceous glands, and is supplied by small arteries.

Topical Imiquimod may fight vascular tumors by affecting blood vessels or the immune system, low iron might be linked to some hair loss, removing the top skin layer helps vitamin C get in, genetic testing helps diagnose skin conditions, and too much iron could worsen skin inflammation.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Ethanol over 50% helps minoxidil absorb better into skin.

Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.

Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.

Microparticles help caffeic acid stay longer in hair follicles for better treatment of folliculitis.

Pathologic tissues have more soluble proteins than normal tissues.

Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.

Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.

Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.

Combining physical dermabrasion with chemical peeling is more effective for skin treatment than chemical peeling alone.