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    Glossary Human Outer Root Sheath Cells

    cells in hair follicle's outer layer aiding growth and regeneration

    Human Outer Root Sheath Cells are a type of cell found in the outer layer of the hair follicle. These cells play a crucial role in the growth and regeneration of hair, as they provide structural support and house stem cells that can differentiate into various cell types needed for hair production.

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    1. Wnt/β‐catenin and ERK pathway activation: A possible mechanism of photobiomodulation therapy with light‐emitting diodes that regulate the proliferation of human outer root sheath cells Lasers in Surgery and Medicine · 2017 · 43 citations
    2. VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway Molecular Biology Reports · 2012 · 23 citations
    3. Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles International journal of molecular sciences · 2021 · 14 citations
    4. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    5. Wnt/β-catenin and ERK pathway activation: The possible mechanism of various light-emitting diode light regulates the proliferation of human outer root sheath cells Journal of The American Academy of Dermatology · 2017
    6. P140 Light-emitting diode light regulates the proliferation of human outer root sheath cells via Wnt/β -catenin and ERK pathway 프로그램북(구 초록집) · 2016
    7. Human Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Papilla Cell Tissue Engineering and Regenerative Medicine · 2020 · 9 citations
    8. Effects of Human Hair Outer Root Sheath Cell- and Human Bone Marrow Mesenchymal Stem Cell-Derived Exosomes on Human Hair Follicle Stem Cells Current Stem Cell Research & Therapy · 2026
    9. A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells 1989 · 2 citations
    10. Organotypic culture of outer root sheath cells from human hair follicles using a new culture device In Vitro Cellular & Developmental Biology - Plant · 1987 · 35 citations
    11. miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells Frontiers in cell and developmental biology · 2020 · 18 citations
    12. Immunolocalization of telomerases in human hairs identifies proliferating cells in the bulb matrix and outer root sheath 2024
    13. FORMATION OF A REGULAR NEO-EPIDERMIS BY CULTURED HUMAN OUTER ROOT SHEATH CELLS GRAFTED ON NUDE MICE Transplantation · 1995 · 14 citations
    14. Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro Molecular Medicine Reports · 2017 · 5 citations
    15. Interferon β Secreted from Human Hair Dermal Papilla Cells Inhibits the Growth of Outer Root Sheath Cells Cultured in Vitro Biochemical and biophysical research communications · 2002 · 13 citations
    16. Trichilemmoma.Cell biology of the normal human outer root sheath. Skin Cancer · 1995
    17. Keratins of the human hair follicle: “Hyperproliferative” keratins consistently expressed in outer root sheath cells in vivo and in vitro Differentiation · 1987 · 135 citations
    18. Human hair follicle cells of outer root sheath maintain their genuine keratin expression in vitro 1986 · 1 citations
    19. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
    20. Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells Biochemical and Biophysical Research Communications · 2007 · 34 citations
    21. Novel ALK5 inhibitor TP0427736 reduces TGF-β induced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles Pharmacological Reports · 2017 · 14 citations
    22. Effect of Minoxidil Sulfate on the Growth of Human Anagen Hair Follicles Grown in Collagen Gels, and on the Colony Growth of Human Cultured Outer Root Sheath Cells in vitro. The Nishinihon Journal of Dermatology · 1992 · 1 citations
    23. [An immunohistochemical study on cell differentiation in the outer root sheath of the normal human anagen hair follicles with antikeratin monoclonal antibodies]. PubMed · 1990 · 6 citations
    24. Sex hormones and antiandrogens influence in vitro growth of dermal papilla cells and outer root sheath keratinocytes of human hair follicles 1993 · 9 citations
    25. Effect of minoxidil sulfate and pinacidil on single potassium channel current in cultured human outer root sheath cells and dermal papilla cells Journal of Dermatological Science · 1994 · 16 citations
    26. Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes Cell and Tissue Research · 1994 · 36 citations
    27. Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells Experimental Dermatology · 2012 · 6 citations
    28. Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment Scientific Reports · 2019 · 5 citations
    29. Sex Hormones and Antiandrogens Influence In Vitro Growth of Dermal Papilla Cells and Outer Root Sheath Keratinocytes of Human Hair Follicles. 1993 · 12 citations
    30. Improved isolation of outer root sheath cells from human hair follicles and their proliferation behavior under serum-free condition Biotechnology and Bioprocess Engineering · 2007 · 13 citations