Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.
17 citations,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
[object Object] 238 citations,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
September 2023 in “Frontiers in bioengineering and biotechnology” JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.
29 citations,
November 2011 in “Veterinary pathology” The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.
188 citations,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
98 citations,
June 2008 in “Human mutation” A genetic change in the EDAR gene causes the unique hair traits found in East Asians.
6 citations,
June 2011 in “Pharmacognosy Journal” Many products for hair re-growth exist, but a perfect treatment without side effects has not yet been found.
1 citations,
April 2023 in “Scientific Reports” Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
7 citations,
January 2019 in “Annals of dermatology/Annals of Dermatology” Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.
378 citations,
November 2011 in “Human reproduction update” Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
11 citations,
August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
88 citations,
May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
88 citations,
February 2011 in “Journal of Dermatological Science” Minoxidil helps hair growth by activating the β-catenin pathway.
8 citations,
April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
11 citations,
October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
2 citations,
May 2001 in “Current problems in dermatology” The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.
284 citations,
February 2008 in “Pediatrics” Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
53 citations,
July 2016 in “Cosmetics” Future hair cosmetics will be safer and more effective.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
14 citations,
February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
5 citations,
January 2021 in “iScience” Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
7 citations,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
August 2023 in “Scientific reports” Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
43 citations,
February 2013 in “Developmental dynamics” Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.
4 citations,
July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
[object Object] 29 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.