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Immune cells affect hair growth and could lead to new hair loss treatments.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Different hair loss types need accurate diagnosis for proper treatment.

Local healers in Addis Ababa use 81 medicinal plants, mainly from the Asteraceae family, to treat skin and general diseases, with Echinops kebericho being an endangered plant important in their practices.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Probiotic bacteria improved skin and hair health in aged mice.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Using stem cells from fat tissue can significantly improve wound healing in dogs.

Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.

New protein changes may be involved in the immune attack on hair follicles in alopecia areata.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Endocrine disruptors may cause early hair loss.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

The Hairless gene is crucial for healthy skin and hair growth.

Enzymes that change arginine to citrulline are important for skin barrier and hair formation, and their malfunction can lead to skin conditions and hair disorders.

Mesenchymal stem cells show promise for effective skin repair and regeneration.