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The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Edar signaling is crucial for controlling hair growth and regression.

Hair follicle stem cells help skin heal and grow during stretching.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Genetic variations affecting skin structure play a key role in severe acne.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

A mother's iron levels early in pregnancy can influence the DNA makeup of her child, potentially affecting the child's health.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Edar signaling is crucial for proper hair follicle development and function.

The study concluded that genetic mutations affect human hair diseases and identified key genes and pathways involved in hair growth and cycling.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

The enzyme is crucial for skin cell development and can be activated without proteolytic activation.

The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.

CTLA4 gene variants are not linked to alopecia areata in Monterrey's Mexican population.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.

Identified genes linked to male-pattern baldness may help develop new treatments.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.