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This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.

This study found that mimicking the XPD point mutation in mice resulted in trichothiodystrophy-like symptoms, supporting the role of basal transcription and DNA repair defects in the disease.

This study found several microRNA-related genetic variants linked to epithelial ovarian cancer risk, with a notable association at the 17q21.31 region, suggesting potential new susceptibility genes.

This article discusses methods to measure comedogenesis in acne through the presence of microcomedones and reports no new clinical results; the authors outline a skin surface biopsy technique using cyanoacrylate gel.

In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.

This study identified WNT10A as crucial for adult epithelial cell proliferation and differentiation, suggesting β-catenin pathway activation may help address regenerative defects in WNT10A mutation patients.

This systematic review suggests that current evidence does not support routinely discontinuing gender-affirming hormone treatments before surgery, especially testosterone and spironolactone, due to limited data on related perioperative risks.

The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.

This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.

In vitro skin models are improving but still need more innovation to fully replicate human skin.

This study found that azelaic acid entrapped in transethosomes exhibited enhanced antidermatophyte activity and improved treatment outcomes in guinea pig models of dermatophytosis compared to free azelaic acid.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

This study found that PEGylation of nanoparticles enhances their penetration into hair follicles, with higher molecular weight PEG resulting in deeper follicular delivery.

This study explored the wound healing potential of a natural marine soft coral-derived nanoparticle-based gel in a diabetic excision wound model, finding it effectively regulates proinflammatory cytokines and inhibits enzymes related to wound healing.

This review highlights the significant negative impact of alopecia areata on quality of life, mental health, and work, calling for individualized approaches and effective treatments to mitigate these effects.

This study found that dutasteride treatment in pregnant mares significantly increased progesterone concentrations but did not alter gestational length or neonatal outcomes.

In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.

This study found that mice lacking the CXCR2 receptor regenerated tissue scarlessly in various injury models and that administering plasma or G-CSF from these mice to wild-type mice also reduced scarring, suggesting potential therapeutic strategies to improve human skin wound healing.

This study found that the MIR34A rs2666433 (A/G) variant is linked to increased risk and severity of alopecia areata, and high circulatory miR-34a levels may play a role in the disease's pathogenesis.

This study reported that a large proportion of US adults with physician-diagnosed alopecia areata experience substantial emotional and mental health comorbidities and report significant stigma across all disease severities, yet few are receiving counseling or therapeutic intervention.

This study found that SYP123 and VAMP727 are involved in the secretion and transport of inner cell wall components, which is crucial for hardening the root hair shank in Arabidopsis.

Green algae can break down finasteride, reducing environmental harm.

In this study, dermatophytosis was prevalent among 52% of dogs and 70% of cats with skin lesions, with younger animals facing higher infection risks; combined itraconazole, clotrimazole, supportive care, and vaccination led to the fastest recovery.

In this study, the authors developed a medicated face mask using electrospun fibers to deliver the active compound Eflornithine hydrochloride for managing hirsutism. The mask showed promising drug release characteristics, a high safety profile, and reduced hair growth in mice.

This study found that auxin regulates reactive oxygen species-mediated root hair growth by activating transcription factors and enzymes that affect cell elongation.

This review discusses infertility in polycystic ovary syndrome and therapeutic options, without reporting new results; it underscores the importance of personalized treatment plans based on patient needs and disease characteristics.

This study reviewed tinea capitis cases in children at a dermatology clinic from 1977-1988, finding Trichophyton violaceum as the most common pathogen, with Moroccan immigrant children being the largest affected group.

This study identified a new ovine KRTAP21-1 gene variant in sheep, with wool yield affected by the variant, suggesting its potential as a genetic marker for improving wool production.

This study found that genetic variation in the KRTAP21-2 gene among crossbred Merino lambs was associated with differences in wool traits, particularly mean staple length.