January 2026 in “Journal of Materials Chemistry B” In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.
12 citations
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August 1984 in “Genetics Research” In this study, researchers found that the naked (N) gene in mice indirectly affects the synthesis of structural proteins in mouse hair, resulting in reduced high tyrosine protein content and unusual amino acid compositions.
2 citations
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July 2020 in “International journal of regenerative medicine” This study suggests that autologous fat transfer can significantly enhance hair growth in patients with scarring alopecia, offering more consistent and predictable results when combined with hair transplantation.
1 citations
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January 2017 in “International Journal of Dermoscopy” This study observed that dermoscopy is a valuable tool for hair transplant surgeons to evaluate and improve the aesthetic outcomes and address technical errors in transplant procedures.
December 2024 in “BMC Plant Biology” This study examined Prunus mira populations in the Qinghai-Tibetan Plateau and found high genetic diversity and substantial phylogeographic structure, suggesting geographic isolation limits gene flow; the researchers propose conservation strategies to preserve genetic resources.
July 2004 in “Transplantation” This study found that enalapril treatment reduced hematocrit levels in posttransplant erythrocytosis patients and increased transferrin saturation index and ferritin levels in those with iron deficiency among long-term renal transplant recipients.
September 2025 in “Frontiers in Pharmacology” This study suggests that P. orientalis leaf-derived EVs could offer anxiolytic, antidepressant, and sleep-inducing benefits by affecting neurotransmitter levels and reducing inflammation, particularly when administered intranasally.
February 2024 in “Endocrinology and Disorders” This article compiles evidence on prescribing estrogen for hormonal imbalance in women, emphasizing it should be personalized and carefully managed by healthcare providers based on individual cases.
August 2023 in “Clinical Endocrinology and Metabolism” This article provides evidence on when it is appropriate to prescribe hormone therapy for women by reviewing cases from the author's practice and international literature, emphasizing the importance of primary care in managing hormonal imbalances.
This study found that in vitro, EGCG may help treat colorectal cancer by targeting iron chelation and the ER stress pathway, leading to apoptosis in cancer cells while sparing normal cells.
49 citations
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July 2004 in “Anesthesiology” This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
19 citations
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January 2023 in “Genes” This study identified genomic regions and genes associated with wool, live weight, body condition, and reproduction traits in Uruguayan Merino sheep, highlighting potential genetic factors influencing these characteristics.
77 citations
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July 2020 in “Cell” This study found that sympathetic nerves and arrector pili muscles form a niche that modulates hair follicle stem cell activity, revealing their role in hair follicle regeneration.
66 citations
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May 2012 in “Scientific Reports” This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.
22 citations
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September 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This review highlights the possible role of T regulatory cells in the immune-related mechanisms of alopecia areata but reports no new clinical findings.
21 citations
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October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified specific germline and somatic mutations in the Phospholipase C Delta 1 gene as high-risk factors for developing hereditary trichilemmal cysts, involving a monoallelic two-hit mechanism.
6 citations
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January 2024 in “Annals of Dermatology” In this study, treatment with recombinant DKK2 was shown to significantly stimulate hair progenitor cell growth and enhance hair shaft elongation in ex vivo human hair follicle cultures by activating the Wnt/ẞ-catenin signaling pathway, suggesting a potential role for DKK2 in promoting hair growth.
3 citations
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April 2016 in “PubMed” This study found that a twice-daily regimen of 5% minoxidil foam combined with a botanical hair solution significantly improved hair growth and appearance in men with mild to moderate androgenic alopecia over 12 weeks.
2 citations
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January 2023 in “BMC plant biology” This study found that root hair length and density in rice are controlled by distinct genomic regions, with 18 regions identified but no overlap between the traits.
2 citations
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April 2016 in “PubMed” This study found that a 12-week regimen of 2% minoxidil combined with a botanical hair solution improved hair growth and patient satisfaction for female pattern hair loss, aiding treatment adherence.
December 2025 in “Gastroenterology Insights” This study found that IBS is positively associated with psoriasis, rosacea, and urticaria, but inversely associated with acne and vitiligo.
January 2025 in “Diagnostics” This study found that a new three-dimensional high-frequency ultrasound (3D-HFUS) can successfully visualize skin tumors and inflammatory hair diseases, offering promising noninvasive diagnostic and evaluation capabilities compared to traditional two-dimensional methods.
December 2023 in “The journal of cell biology/The Journal of cell biology” This study developed the mTurquoise2-Col4a1 mouse model and used fluorescent tagging of collagen IV to offer new insights into basement membrane dynamics during hair follicle budding, revealing that basement membranes are flexible and stable structures in developing skin tissue.
October 2010 in “International journal of radiation oncology, biology, physics” In this randomized study, patients with early favorable Hodgkin lymphoma showed similar complete remission and survival rates whether receiving 2 or 4 cycles of ABVD and 20 Gy or 30 Gy IFRT, though reduced toxicity was associated with fewer cycles and lower radiation doses.
104 citations
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May 2003 in “Endocrinology” This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.
27 citations
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June 2023 in “Nature” In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
9 citations
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December 2022 in “Antibiotics” This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
3 citations
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July 2023 in “Biomolecules” This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.
3 citations
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January 2015 in “Dermatology Online Journal” This case report highlights a patient whose essential syphilitic alopecia was the only symptom of syphilis, which improved after benzathine penicillin treatment, emphasizing alopecia as a potential sign of syphilis.