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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Certain changes in the SHBG gene may increase the risk of PCOS in Iraqi women.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Lowering testosterone speeds up wound healing in male mice.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Hair loss improved with treatment and successful transplant.

Heavy metals like arsenic, cadmium, and lead can increase cancer risk and worsen outcomes.