January 2020 in “International Journal of Research” High testosterone increases heart disease risk in women with PCOS.
2 citations,
January 2018 in “Biology and medicine” High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
April 2019 in “Journal of the Endocrine Society” Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.
April 2019 in “Journal of the Endocrine Society” A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.
6 citations,
January 2019 in “F1000Research” High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
2 citations,
September 2020 Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.
September 2024 in “International Journal of Molecular Sciences” High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
25 citations,
August 2006 in “Human Reproduction” Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
9 citations,
January 2007 in “Endocrine Practice” A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.
October 2023 in “Journal of the Endocrine Society” A woman's ovarian fibroma caused high testosterone levels, which normalized after surgery.
August 2013 in “Fertility and sterility” Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
16 citations,
August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
3 citations,
February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
2 citations,
November 2019 in “Case reports in women's health” Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.
January 2016 in “AACE Clinical Case Reports” Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.
8 citations,
April 2019 in “Journal of the Endocrine Society” Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
2 citations,
August 2011 in “Revista Medica De Chile” A postmenopausal woman's high testosterone levels and symptoms improved after removing a tumor from her ovary.
January 2023 in “Case Reports in Obstetrics and Gynecology” A woman's high testosterone levels and related symptoms improved after ovary removal surgery.
12 citations,
March 2018 in “Medicine” A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
4 citations,
June 2005 in “Andrology” A woman's diabetes improved after removing ovarian tumors that caused high testosterone levels.
6 citations,
December 2015 in “JAMA” The woman's high testosterone levels indicated PCOS, leading to treatment that improved her symptoms.
November 2018 in “Endocrine Abstracts” A woman's high testosterone levels were caused by a rare ovarian tumor, not the initially diagnosed condition.
11 citations,
November 2006 in “Journal of Veterinary Diagnostic Investigation” An alpaca acted like a male and couldn't have babies because of a benign tumor in its ovary that caused high testosterone levels.
April 2019 in “Journal of the Endocrine Society” A woman's severe insulin resistance improved with treatment, but she still had high testosterone levels due to ovarian issues.
47 citations,
January 2001 in “Journal of Investigative Dermatology” High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
January 2021 in “Case Reports” A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.
The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
April 2020 in “Journal of the Endocrine Society” A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.
January 2007 in “Annals of The Royal College of Surgeons of England” Removing a hormone-producing adrenal tumor can stop hair loss in women with high testosterone levels.
April 2019 in “Journal of the Endocrine Society” The study found that imaging might miss small ovarian tumors causing high testosterone, and suggested using certain testosterone levels and treatment responses to identify these tumors.