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    Glossary High Mobility Group Box 1

    protein involved in DNA regulation and immune response signaling

    High Mobility Group Box 1 (HMGB1) is a protein that plays a crucial role in regulating DNA structure and function. It is involved in various cellular processes, including DNA repair, transcription, and inflammation. HMGB1 can act as a signaling molecule outside the cell, where it can trigger immune responses and is often associated with inflammatory diseases and tissue damage.

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    1. Investigating Alopecia Areata and its Connection to The High-Mobility Group Box 1: Review Article The Egyptian Journal of Hospital Medicine · 2021
    2. Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles Scientific reports · 2017 · 22 citations
    3. HMGB1 promotes hair growth via the modulation of prostaglandin metabolism Scientific Reports · 2019 · 12 citations
    4. RAGE and Its Ligands in Melanoma InTech eBooks · 2015 · 1 citations
    5. The incidence of diplopia following coronal and translid orbital decompression in Graves' orbitopathy Eye · 1998 · 65 citations
    6. Fertility and Sterility Vol 101 No 4, April 2014 Fertility and Sterility · 2014
    7. Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights Biomolecules · 2025
    8. S100A6 Protein—Expression and Function in Norm and Pathology International Journal of Molecular Sciences · 2023 · 21 citations
    9. The exploration of mitochondrial‐related features helps to reveal the prognosis and immunotherapy methods of colorectal cancer Cancer Reports · 2023 · 2 citations
    10. What’s Diet Got to Do With It? Basic and Clinical Science Behind Diet and Acne Cutis · 2022 · 2 citations
    11. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair Nature Communications · 2019 · 87 citations
    12. The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility Journal of Assisted Reproduction and Genetics · 2021 · 17 citations
    13. ‘The psychosocial burden of alopecia areata and androgenetica’: a cross‐sectional multicentre study among dermatological out‐patients in 13 European countries Journal of the European Academy of Dermatology and Venereology · 2019 · 46 citations
    14. Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004 · 47 citations
    15. Optimization of menthol-loaded nanocapsules for skin application using the response surface methodology Journal of drug delivery science and technology · 2019 · 25 citations
    16. γδ17 T cell-stromal networks modulate matrix composition and vascularity in foreign body response 2026 · 1 citations
    17. Novel anti-aging gene NM_026333 contributes to proton-induced aging via NCX1-pathway 2018 · 10 citations
    18. A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia Journal of Nutrition Health & Aging · 2013 · 211 citations
    19. Serum Levels of VWF, t-PA, TNF-α, and ICAM-1 in Patients Receiving Hemocoagulase Combined with Platelet-Rich Plasma during Total Hip Replacement Genetics Research · 2022 · 2 citations
    20. The Rotterdam Study: 2016 objectives and design update European Journal of Epidemiology · 2015 · 336 citations
    21. Effect of ethanol Adiantum capillus-veneris extract in experimental models of anxiety and depression Brazilian Journal of Pharmaceutical Sciences · 2019 · 7 citations
    22. Deciphering the cellular landscape and genetic underpinnings of fiber diameter determined by dermal papilla cells in fine-wool sheep Frontiers in Cell and Developmental Biology · 2026
    23. Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters BMC Genomics · 2018 · 16 citations
    24. Dermatologie care behind bars Journal of The American Academy of Dermatology · 1988 · 21 citations
    25. Skin Disorders in Athletes: Professional and Recreational Sports Springer eBooks · 2018
    26. Male hormonal contraception: looking back and moving forward Andrology · 2015 · 23 citations
    27. Effects of Decursin and Angelica gigas Nakai Root Extract on Hair Growth in Mouse Dorsal Skin via Regulating Inflammatory Cytokines Molecules · 2020 · 22 citations
    28. Management of congenital ichthyoses: European guidelines of care, part two British Journal of Dermatology · 2018 · 66 citations
    29. Phytochemical, Toxicological and Pharmacological Studies of <i>Asiasari Radix</i> et Rhizoma: A Review Tropical Journal of Pharmaceutical Research · 2015 · 17 citations
    30. The Rotterdam Study: 2018 update on objectives, design and main results European Journal of Epidemiology · 2017 · 359 citations