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Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

New treatments for male hypogonadism are effective and should be personalized.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Diet, especially dairy and high-sugar foods, can cause acne.

Hair loss in women may have causes other than hormones.

Certain drugs that block specific enzymes can help treat prostate diseases.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Some drugs can cause hair loss, excessive growth, or color changes, often reversible but sometimes permanent.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Multimodal primary treatment improves survival in premenopausal breast cancer patients and is also beneficial for postmenopausal women.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.

Some breast cancer patients on hormonal therapy may develop male or female pattern hair loss, which can sometimes be improved with topical treatments.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.