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The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.

Hysteroscopic surgery is better than hysterectomy for treating dysfunctional uterine bleeding due to fewer complications and quicker recovery, with high satisfaction in both treatments.

Topical imiquimod use for treating a cervical lesion might cause delayed hair loss.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.

Hair restoration has evolved from surgery to drugs to potential gene therapy, with improved results and ongoing research driven by high demand.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

The congress showed that psychological therapy can help skin condition patients, social media affects acne stigma, education improves atopic dermatitis, and patient satisfaction in dermatology is high, especially with good doctor engagement.

Spironolactone use is not linked to an increased risk of breast cancer, but caution is advised for high-risk patients.

Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.

The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

SHBG may be a useful early indicator and treatment target for PCOS.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.

PCOS affects many women and requires early detection and symptom management.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.

A woman's hair loss was linked to a rare hormone-secreting ovarian tumor, treated with surgery and hair loss medication.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.