January 2025 in “International Journal of Veterinary Science” In this animal study, hibiscus leaf simplicia ointment was found to protect red blood cell levels and promote better hair growth in UV-exposed rats, though it did not maintain normal skin histology; the ointment showed no significant acute dermal toxicity.
16 citations
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September 2018 in “Journal of Ethnopharmacology” This review discusses the role of inheritance, androgens, and microinflammation in androgenetic alopecia and suggests some plant-based folk remedies may help address these factors but reports no new clinical results.
December 2022 in “Journal of Tropical Pharmacy and Chemistry” This study evaluated a hair tonic formulated from oil palm leaf extract, finding it demonstrated very strong antioxidant activity and could prevent hair decolorization from sun exposure, with effective concentrations ranging from 25 to 200 ppm.
May 2023 in “Pharma xplore : jurnal sains dan ilmu farmasi” In an animal study, researchers found that a hair tonic containing a 1:1 ratio of kelor and rambutan leaf extracts led to similar hair growth in rabbits compared to a minoxidil control, with average hair lengths of 3 cm versus 2.025 cm, respectively.
March 2023 in “Jurnal Ilmiah Medicamento” In this study, herbal hair tonic made from Usada Bali ingredients significantly increased hair growth in mice without causing skin irritation compared to a negative control.
September 2024 in “Sasambo Journal of Pharmacy” This study formulated and tested a pomegranate leaf shampoo with antifungal properties, identifying an optimal composition of 5.5% SLS and 15.5% cocamide DEA, showing good foam stability, appropriate pH, and viscosity in lab tests.
October 2025 in “International Journal For Multidisciplinary Research” This review study found strong scientific support for traditional Indian hair care practices, demonstrating that herbs like Amla, Bhringraj, and Ashwagandha have beneficial effects on hair growth and scalp health, backed by technological advancements that enhance their therapeutic potential.
November 2017 in “Asian journal of pharmaceutical and clinical research” This study predicted that 6-hydroxy genistein, coreximine, and scoulerine from Dadap leaves may act as anti-alopecia agents by interacting with JAK2, but further in-vivo testing is needed.
2 citations
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January 2025 in “International Journal of Pharmaceutical Research and Applications” This study formulated an herbal shampoo using natural extracts and compared its physicochemical properties, such as pH and foam consistency, with commercial shampoos, finding that both performed similarly in conditioning tests conducted with twenty volunteers.
35 citations
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November 2024 in “Gels” This review discusses hydrogel-forming microneedles for non-invasive drug delivery in dermatology and reports no new clinical results, emphasizing their promise in improving treatment adherence and patient comfort.
October 2022 in “International journal of pharmaceutical sciences review and research” This study compared the antioxidant and antidiabetic activities of Hibiscus rosa-sinensis leaf extract and Eclipta alba bark extract, finding that Hibiscus rosa-sinensis exhibited greater antidiabetic activity, whereas Eclipta alba demonstrated stronger antioxidant activity.
59 citations
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August 2014 in “International Journal of Biological Macromolecules” In this study, the researchers optimized the extraction conditions for crude polysaccharide from Hibiscus rosa-sinensis leaves, achieving a yield of 9.66% and demonstrated strong antioxidant activities in vitro.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, herbal hair oil formulated from Murraya koenigii, Hibiscus rosasinensis, and Lawsonia inermis showed promising properties such as good pH, acceptable viscosity, and stability at room temperature, suggesting potential for hair growth promotion in future formulations.
128 citations
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September 2003 in “Journal of Ethnopharmacology” This study found that the petroleum ether extract from the leaves of Hibiscus rosa-sinensis demonstrated more effectiveness in promoting hair growth in rats compared to the extract from its flowers.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
November 2023 in “International Journal For Multidisciplinary Research” This review explores how herbal hair oils made from ingredients like amla and hibiscus may offer benefits such as reducing hair loss and dandruff, but these are summarized from existing research rather than new experimental data.
June 2026 in “International Journal of Innovative Science and Research Technology (IJISRT)” This study aimed to create and evaluate a herbal hair serum containing curry leaf and hibiscus extracts, formulated to promote hair growth and reduce hair loss using castor and almond oils as the base.
2 citations
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February 2019 in “JOJ dermatology & cosmetics” The study found that Anagen grow, a herbal serum, promotes hair growth elongation and may inhibit the alpha reductase enzyme, suggesting it as a safe, effective alternative to finasteride and beneficial alongside minoxidil for reducing scalp dryness.
June 2026 in “International Journal for Research in Applied Science and Engineering Technology” This study formulated and evaluated a polyherbal hair growth oil using plants like Amla and Neem. The oil showed desirable physicochemical properties, stability, safety, and potential effectiveness, representing a promising natural alternative to synthetic hair care products for promoting healthy hair and scalp protection.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review assessed a traditionally prepared herbal hair oil, finding it exhibited favorable physicochemical properties and stability, with no skin irritation, suggesting it may be a safe natural alternative to synthetic hair care products for promoting healthy hair and scalp.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlighted the potential benefits of herbal hair oils as a natural alternative to synthetic hair care products, noting that a traditionally prepared formulation demonstrated favorable physicochemical properties and no skin irritation, while promoting healthy hair and scalp.
July 2025 in “Research Journal of Science and Technology” This study highlights the increasing consumer preference for herbal and organic hair care products due to their minimal side effects, and it describes various natural ingredients like fenugreek and flaxseed that may help treat hair disorders and promote healthy hair growth.
October 2019 in “Innovative Journal of Medical and Health Science” This study suggests that certain herbs may reverse the catagen phase in hair growth, potentially providing a treatment approach for alopecia.
March 2022 in “Journal of drug delivery and therapeutics” Sea hibiscus leaf extract at 30% concentration in a hair tonic significantly increased hair growth in guinea pigs.
1 citations
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August 2021 in “International journal of scientific research in science and technology” This study evaluated a polyherbal hair oil, containing natural ingredients like Hibiscus and Aloe Vera in a coconut oil base, for its phytochemical properties, antimicrobial activity, and potential to reduce dandruff and hair loss while promoting hair growth.
This study found that a 10% hibiscus leaf extract hair tonic demonstrated better hair growth activity than 2% minoxidil in rabbits but caused eye irritation.
January 2020 in “Archives of Pharmacy Practice” This study found that Hibiscus rosa-sinensis leaf extract promoted hair growth in rats more effectively than its flower extract, suggesting its potential as a natural alternative for hair growth treatments.
This study found that creambath preparations with waru leaf extract accelerated hair growth in New Zealand White rabbits, though none matched the positive control; the 37.5% concentration increased hair weight effectively.
In this experimental study, hibiscus leaf extract at a 30% concentration showed effectiveness in promoting hair growth on guinea pigs, with measurable increases in hair length and weight by the 21st day.
January 2017 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” In this study, administering varying doses of Hibiscus rosa-sinensis leaf water extract to BALB/c mice for 28 days did not result in significant changes in haematological parameters, body weight, or food consumption, suggesting no noticeable toxicity effects in the tested conditions.