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Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Doctors linked maternal drinking to infant mortality and national decline, leading to public awareness and changes in law.

Cyclosporin doesn't stop hair loss.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.