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This review discusses the role of keratins in epithelial cell stress protection and cancer, highlighting their potential as multifunctional regulators and diagnostic markers, without presenting new research findings.

This study found that keratin derivatives with functionalized thiol groups improved binding to both natural and bleached hair fibers, suggesting a promising strategy for enhancing keratin's durability in hair repair.

This study identified a missense mutation in the keratin 71 gene as the cause of autosomal dominant woolly hair/hypotrichosis in a Japanese family, marking the first human mutation in KRT71 linked to a hair disorder.

This study identified a 69 bp deletion in the KRT75 gene as the cause of the frizzle feather trait in chickens, affecting feather curling.

In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.

This study proposes a new method to selectively isolate keratin-associated proteins and keratin from human hair, suggesting that KAPs may support keratin fibers in hair structure.

This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.

This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.

This study presents recombinant human hair keratins K31 and K81, observing novel nanostructures from their self-assembly and emphasizing disulfide crosslinking's role in this process.

This study reported that using 2D solid-state NMR techniques on extensively labeled mouse fur improves resolution in detecting chemical shifts and secondary structure features, potentially aiding the analysis of the effects of commercial or therapeutic treatments on specific amino acids.

This article reviews the complex structure and molecular composition of hair keratins, highlighting their self-assembly process and implications for keratin extraction techniques, but reports no new experimental results.

This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.

This study found that mutations in certain keratin genes significantly affect wool traits in Chinese Merino sheep, suggesting these genes could be important for sheep breeding to improve wool quality.

This study identified and updated the annotation of 61 keratin genes in dogs and horses, improving the genome annotation in these species through RNA-seq data comparison.

The researchers reported that keratin 33A is a structural protein specific to goat cashmere hair, with increased winter expression in high-cashmere-producing breeds.

This study utilized advanced imaging techniques to quantify hair damage and dye uptake dynamics, revealing that compound penetration in hair is influenced by molecule size and lipophilicity.

Keratins are crucial for cell structure, growth, and disease risk.

This study observed that genetic variation in the ovine KRTAP22-1 gene is linked to increased wool yield and decreased fiber curvature in sheep, indicating its potential use in breeding programs.

In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.

This study found that polymorphisms in the KAP8.2 gene in Chinese Inner Mongolia cashmere goats are associated with variations in cashmere fibre diameter, suggesting its potential as a molecular marker for this trait.

This review explains the mechanical composition and molecular interactions that determine hair's mechanical properties, without providing any new experimental findings.

This article discusses the importance of integrating clinical observations with laboratory research, emphasizing the need for clinicians to collaborate with researchers to address medical problems.

This review discusses recent advances in the genetic understanding of inherited hair and nail disorders and reports no new clinical results.

This chapter reviews hair anatomy, hair shaft structure, and various cosmetic treatments that can alter or damage hair, but it presents no new research findings.

This review discusses the development and types of hair and nails as skin appendages and reports no new research findings.

This study found that structural defects in the hair shafts of sighthounds with bald thigh syndrome are related to a downregulation of genes and proteins essential for hair shaft formation.

This paper reviews the genetic aspects of hair disorders and suggests that understanding these genes could advance treatment and diagnosis; it reports no new experimental findings.

This study observed that the molecular structure of keratins in hair fibres' discrete transition zone differs in breast cancer patients, with altered lipid ester absorption bands reverting post-cancer removal.

This biographical abstract highlights George Rogers' pioneering contributions to the understanding of keratin molecular structure and keratinisation biochemistry, including the application of electron microscopy to hair ultrastructure and the discovery of enzymes and gene transcription processes relevant to keratin proteins.

This study identified KRT82 as a significant Alopecia Areata risk gene, finding that rare damaging variants are linked to elevated immune cell infiltration around hair follicles in affected individuals.