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This study found that a keratin mutation may cause diffuse partial woolly hair associated with loose anagen hair syndrome in some families, but other genetic factors could play a role in different cases.

This article reviews the genetic and protein interactions involved in hair growth, highlighting regulatory sequences, expression patterns, and potential genetic modifications, but presents no new experimental findings.

This review identifies genetic mutations associated with congenital hair loss disorders in Japanese populations, particularly highlighting common LIPH gene mutations linked to woolly hair/hypotrichosis, and reports no new clinical results.

This study analyzes the fine structure and protein distribution in monotreme hairs, finding similarities with other mammals and detailing unique immunocytochemical features in their inner root sheaths.

Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.

In this study, researchers explored the molecular and cellular traits of avian reticulate scales, finding that they lack localized stem cell niches for regeneration, unlike other scale types, leading to repair but not regeneration after wounding.

This article discusses a hypothesis on the development and evolution of scales, hairs, and feathers from fish to amniotes, based on regions of dermo-epidermal interactions in skin, but reports no new findings.

Pax9 is crucial for proper tongue surface development and preventing skin-like changes.

This study found that keratin and other hair proteins in humans are extensively modified posttranslationally, which helps explain the structural characteristics of mature hair.

This review discusses the evolution of modern shampoos from basic cleansing agents to products with specific therapeutic uses and emphasizes the importance of dermatologists understanding shampoo mechanisms and appropriate selection for scalp and hair health.

This review discusses the assessment and management of common causes of pediatric alopecia, highlighting the importance of dermatologist referral for unclear diagnoses, treatment failures, or scarring alopecia, and reports no new clinical findings.

This review discusses keratin disorders and potential RNA interference therapeutics, reporting no new clinical findings but highlighting the promise of siRNA for future treatments.

In this study, full-size KRT81 was expressed in both normal breast epithelial and breast cancer cells, and contributed to the migration and invasion abilities of breast cancer cells.

This study used rapid-freezing immunocytochemistry to successfully map the ultrastructural localization of hair keratins in human scalp hair, primarily finding them in macrofibrils in the cortex and endocuticle.

This study found that keratin K14 expression occurs early in epidermal cell differentiation, while a hair-specific keratin is expressed later in hair matrix cells, suggesting developmental divergence between the two cell types.

This study discovered nine human type I hair keratin genes, including a transcribed pseudogene, in a 190 kbp genomic region, revealing three gene subclusters based on sequence homologies.

This study found that recombinant human hair keratin proteins K31 and K81 show greater potential for inducing skin cell differentiation compared to natural keratin coatings.

This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.

This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.

This review discusses the complexity and genetic organization of human keratin gene clusters and addresses the ongoing need for an updated unified naming system; it reports no new clinical results.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

This review examines the potential of K18 as a diagnostic and prognostic marker in epithelial-derived tumors, highlighting its specific expression in tumor tissues and interaction with proteins involved in tumor progression, without reporting new clinical findings.

This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.

This study reports the cloning and sequencing of two type II hair-specific keratin genes, ghHb1 and ghHb6, located on chromosome 12q13, which are expressed during hair growth.

This review discusses current knowledge of keratinocyte stem cell dynamics, including their regenerative roles and potential applications beyond wound healing, but presents no new clinical findings.

This review discusses the potential risks of formaldehyde in hair keratin treatments like Brazilian blow-dry, and reports no new clinical results; it emphasizes the need for greater safety assessments including occupational exposure.

This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.

This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.

In this study, researchers identified two distinct homozygous mutations in the KRT85 gene among consanguineous Pakistani families with pure hair and nail ectodermal dysplasia, highlighting variations in severity and potential impacts on the K85 protein function.

This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.